| Gene Symbol |
ligA
|
| Entrez Gene |
7149372
|
| Alt Symbol |
-
|
| Species |
Escherichia coli
|
| Gene Type |
protein-coding
|
| Description |
NAD-dependent DNA ligase LigA
|
| Other Description |
-
|
| Swissprots |
B7LCF6
|
| Accessions |
B7LCF6 CAU98567 YP_002403714
|
| Function |
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. {ECO:0000255|HAMAP- Rule:MF_01588}.
|
| Top Pathways |
DNA replication, Nucleotide excision repair, Mismatch repair, Base excision repair
|