| Gene Symbol | PROM2 |
|---|---|
| Entrez Gene | 150696 |
| Alt Symbol | PROML2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | prominin 2 |
| Other Description | hPROML2|prominin-2|prominin-like protein 2|prominin-related protein |
| Swissprots | Q2HIX6 A8K2V1 Q8N271 Q8NB84 Q8TAE2 |
| Accessions | AAY14751 EAX10718 EAX10719 EAX10720 EAX10721 EAX10722 Q8N271 AF245303 AAM10541 AF245304 AAM10542 AI928825 AK026052 AK091175 BAC03599 AK091408 BAC03657 AK290366 BAF83055 AK313267 BAG36076 AY358377 AAQ88743 BC025736 BC113877 AAI13878 BC114525 AAI14526 DB003233 XM_005263880 XP_005263937 XM_005263881 XP_005263938 XM_006712301 XP_006712364 XM_011510672 XP_011508974 NM_001165977 NP_001159449 NM_001165978 NP_001159450 NM_144707 NP_653308 |
| Subcellular Location | Apical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Basolateral cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, cilium membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells (By similarity). {ECO:0000250}. |
| Tissue Specificity | Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines. {ECO:0000269|PubMed:12446606, ECO:0000269|PubMed:12514187, ECO:0000269|PubMed:16673119, ECO:0000269|PubMed:17874118}. |
Prominin 2 CRISPR/Cas9 KO Plasmid (h) - sc-407127 from Santa Cruz Biotechnology
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Prominin 2 HDR Plasmid (h) - sc-407127-HDR from Santa Cruz Biotechnology
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Prominin 2 Double Nickase Plasmid (h) - sc-407127-NIC from Santa Cruz Biotechnology
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Prominin 2 Double Nickase Plasmid (h2) - sc-407127-NIC-2 from Santa Cruz Biotechnology
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Prominin 2 CRISPR Activation Plasmid (h) - sc-407127-ACT from Santa Cruz Biotechnology
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Prominin 2 CRISPR Activation Plasmid (h2) - sc-407127-ACT-2 from Santa Cruz Biotechnology
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Prominin 2 Lentiviral Activation Particles (h) - sc-407127-LAC from Santa Cruz Biotechnology
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Prominin 2 Lentiviral Activation Particles (h2) - sc-407127-LAC-2 from Santa Cruz Biotechnology
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Prominin 2 siRNA (h) - sc-94521 from Santa Cruz Biotechnology
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Prominin 2 shRNA Plasmid (h) - sc-94521-SH from Santa Cruz Biotechnology
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Prominin 2 shRNA (h) Lentiviral Particles - sc-94521-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU091311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17461 from Sigma-Aldrich
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PROM2 siRNA (Human) - CRJ5670 from Cohesion Biosciences
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shRNA set against Human PROM2 (NM_144707.2) - SHH383568 from Creative biogene
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Human PROM2 siRNA - orb276171 from Biorbyt
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PROM2 shRNA Plasmid (Human) - CHJ5670 from Cohesion Biosciences
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PROM2 miRNA 3'UTR clone - MiUTR3H-15770 from Creative biogene
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PROM2 miRNA 3'UTR clone - MiUTR3H-15771 from Creative biogene
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