Gene Symbol | sep11 |
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Entrez Gene | 2541925 |
Alt Symbol | med18, pmc6 |
Species | S. pombe |
Gene Type | protein-coding |
Description | mediator complex subunit Pmc6 |
Other Description | - |
Swissprots | Q96VF9 O14198 |
Accessions | CAB10853 O14198 NM_001018796 NP_593364 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:12471453}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Recombinant Schizosaccharomyces pombe Mediator of RNA polymerase II transcription subunit 18(med18) - CSB-YP013651SXV CSB-EP013651SXV CSB-BP013651SXV CSB-MP013651SXV from Cusabio
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Mediator of RNA polymerase II transcription subunit 18 (med18), Recombinant Protein - MBS1219447 from MyBioSource
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