Gene Symbol | Nphs1 |
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Entrez Gene | 64563 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | nephrosis 1, congenital, Finnish type (nephrin) |
Other Description | nephrin|nephrosis 1 homolog, nephrin|renal glomerulus-specific cell adhesion receptor |
Swissprots | Q9QXX7 Q9R044 Q9JIX2 |
Accessions | EDM07757 EDM07758 Q9R044 AF125521 AAF12734 AF161715 AAF14884 AF172255 AAF91086 XM_008759186 XP_008757408 XM_008759187 XP_008757409 NM_022628 NP_072150 |
Function | Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. {ECO:0000269|PubMed:10487848, ECO:0000269|PubMed:11880318}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Located at podocyte slit diaphragm between podocyte foot processes. {ECO:0000269|PubMed:10792613}. |
Tissue Specificity | Strongly expressed in the podocytes of kidney glomeruli (at protein level) and at lower levels in the spleen. {ECO:0000269|PubMed:10487848, ECO:0000269|PubMed:11012881}. |
Rat Nephrin Protein - abx068214 from Abbexa
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Recombinant Nephrin (NPHN) - RPA937Ra01 from Cloud-clone
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Recombinant Rat Nephrin(Nphs1) ,partial - CSB-YP879487RA CSB-EP879487RA CSB-BP879487RA CSB-MP879487RA from Cusabio
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Nephrin (NPHN) - RPU142981 from Biomatik
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Recombinant Rat NPHS1 Protein - NPHS1-4042R from Creative Biomart
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Recombinant Nephrin (NPHN) - RPU42981 from Biomatik
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NPHS1 Recombinant Protein (OPCD05761) - OPCD05761 from Aviva Systems Biology
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Nephrin (Nphs1), partial, Recombinant Protein - MBS1455114 from MyBioSource
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