| Gene Symbol |
SLC7A1
|
| Entrez Gene |
6541
|
| Alt Symbol |
ATRC1, CAT-1, ERR, HCAT1, REC1L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
|
| Other Description |
CAT1|amino acid transporter, cationic 1|ecotropic retroviral leukemia receptor homolog|ecotropic retroviral receptor|ecotropic retrovirus receptor homolog|high affinity cationic amino acid transporter 1|solute carrier family 7 member 1|system Y+ basic amino acid transporter
|
| Swissprots |
P30825 Q5JR50
|
| Accessions |
EAX08443 EAX08444 P30825 AA527433 AB105377 BAQ19762 AF078107 AAC27721 AI362952 AK022999 AK124591 AK312818 BAG35675 AL050021 BC012895 BC033200 BC063303 AAH63303 BC069358 AAH69358 BC115407 AAI15408 BG248687 BM458630 BP356532 DA337847 DA394628 X57303 CAA40560 X59155 CAA41869 XM_005266507 XP_005266564 NM_003045 NP_003036
|
| Function |
High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. {ECO:0000269|PubMed:10485994}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:10485994}; Multi-pass membrane protein {ECO:0000303|PubMed:10485994}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:1718082}.
|
| Top Pathways |
MicroRNAs in cancer
|