MLLT10

Gene Symbol MLLT10
Entrez Gene 8028
Alt Symbol AF10
Species Human
Gene Type protein-coding
Description myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
Other Description ALL1-fused gene from chromosome 10 protein|protein AF-10|type I AF10 protein|type III AF10 protein|type IV AF10 protein
Swissprots Q5JT37 P55197 Q66K63 B1ANA8 Q5VX90
Accessions EAW86161 EAW86162 EAW86163 EAW86164 EAW86165 P55197 AB209755 BAD92992 AF060929 AAC16701 AF060934 AAC16706 AF060935 AAC16707 AF060936 AAC16708 AF060937 AAC16709 AF060938 AAC16710 AK128264 AK301213 BAG62788 AK310803 AL137295 AY598745 AAT47519 BC032532 BC052798 BC065376 BC080577 AAH80577 BC094844 BC129946 BC156206 AAI56207 BC156949 AAI56950 BX640774 CAE45872 BX648210 CAI46260 U13948 AAA79972 XM_005252605 XP_005252662 XM_005252608 XP_005252665 XM_005252609 XP_005252666 XM_011519696 XP_011517998 XM_011519697 XP_011517999 XM_011519698 XP_011518000 XM_011519699 XP_011518001 XM_011519700 XP_011518002 XM_011519701 XP_011518003 XM_011519702 XP_011518004 XM_011519703 XP_011518005 XM_011519704 XP_011518006 XM_011519705 XP_011518007 XM_011519706 XP_011518008 XM_011519707 XP_011518009 XR_930517 NM_001195626 NP_001182555 NM_001195627 NP_001182556 NM_001195628 NP_001182557 NM_001195630 NP_001182559 NM_004641 NP_004632 NM_001009569
Function Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. {ECO:0000269|PubMed:17868029}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10860745}.
Tissue Specificity Expressed abundantly in testis.

AF-10 (N-18) - sc-27083 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AF-10 (N-18): sc-27083. Western blot analysis of AF-10 expression in mouse testis tissue extract.

AF-10 (L-20) - sc-27084 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AF-10 (L-20): sc-27084. Western blot analysis of AF-10 expression in rat testis tissue extract.

AF-10 (HAF10 9A5/2) - sc-53156 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AF-10 (HAF10 9A5/2): sc-53156. Western blot analysis of AF-10 expression in NTERA-2 cl.D1 whole cell lysate (A) and mouse testis tissue extract (B).

AF-10 (HAF10 10D3/8) - sc-53155 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AF-10 (HAF10 10D3/8): sc-53155. Western blot analysis of AF-10 expression in NTERA-2 cl.D1 (A), M1 (B) and K-562 (C) whole cell lysates.

Anti-AF10 antibody - ab71448 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AF10 antibody (ab71448) at 1/100 dilution + Jurkat cell lysate at 12.5 µg

Anti-AF10 antibody - ab64823 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AF10 antibody (ab64823) at 1/500 dilutionLane 1 : CoLo205 cell extract at 5-30ug with no immunizing peptideLane 2 : Jurkat cell extract at 5-30ug with no immunizing peptideLane 3 : Jurkat cell extract with immunizing peptide at 5-10ug

Anti-AF10 antibody - ab56349 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-AF10 antibody [HAF10 10D3/8] - ab16969 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone HAF10 10D3/8

Anti-AF10 antibody [HAF10 9A5/2] - ab16968 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HAF10 9A5/2

Anti-AF10 antibody - C-terminal - ab155205 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AF10 antibody - C-terminal (ab155205) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-MLLT10 Antibody - LS-C63790 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MLLT10 Antibody (C-Terminus, FITC) - LS-C274982 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLLT10 Antibody (C-Terminus, APC) - LS-C274977 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLLT10 Antibody (C-Terminus, AP) - LS-C274979 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLLT10 Antibody (C-Terminus, Biotin) - LS-C274981 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLLT10 Antibody (C-Terminus, Azide-free, HRP) - LS-C274983 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLLT10 Antibody (C-Terminus, PE) - LS-C274984 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLLT10 Antibody (C-Terminus) - LS-C326801 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLLT10 Antibody (Glu237) - LS-C176783 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of AF-10 (E237) pAb in extracts from COLO205 cells.

Anti-MLLT10 Antibody (aa211-260) - LS-C118945 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO205/Jurkat cells, using AF10 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-MLLT10 Antibody (aa200-300) - LS-C340540 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MLLT10 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with Rabbit anti-MLLT10 polyclonal antibody at 1:500 dilution.

Anti-MLLT10 Antibody (clone 6H8) - LS-C198520 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6H8
MLLT10 monoclonal antibody (M01), clone 6H8 Western Blot analysis of MLLT10 expression in HeLa NE.

Anti-MLLT10 Antibody (aa281-293) - LS-C112989 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
MLLT10 antibody (1 ug/ml) staining of Rat Testis lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MLLT10 Antibody (aa998-1027) - LS-C100427 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human testis tissue reacted with MLLT10 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-MLLT10 Antibody (aa1013-1027) IHC-plus™ - LS-B869 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MLLT10 / AF10 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B869 concentration 5 ug/ml.
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