| Gene Symbol | GPI |
|---|---|
| Entrez Gene | 100008744 |
| Alt Symbol | - |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | glucose-6-phosphate isomerase |
| Other Description | AMF|NLK|PGI|PHI|autocrine motility factor|glucose phosphate isomerase|neuroleukin|phosphoglucose isomerase|phosphohexose isomerase |
| Swissprots | Q9N184 Q9N1E2 |
| Accessions | Q9N1E2 AF199601 AAF13713 AF222069 AAF35988 GBCM01001145 NM_001082069 NP_001075538 |
| Function | Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm. Secreted. |
| Top Pathways | Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Amino sugar and nucleotide sugar metabolism, Carbon metabolism, Starch and sucrose metabolism |