Gene Symbol | ZP3 |
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Entrez Gene | 7784 |
Alt Symbol | ZP3A, ZP3B, ZPC, Zp-3 |
Species | Human |
Gene Type | protein-coding |
Description | zona pellucida glycoprotein 3 (sperm receptor) |
Other Description | ZP3A/ZP3B|sperm receptor|zona pellucida glycoprotein 3A (sperm receptor)|zona pellucida glycoprotein 3B|zona pellucida glycoprotein ZP3|zona pellucida protein C|zona pellucida sperm-binding protein 3 |
Swissprots | Q06633 P21754 Q29RW0 |
Accessions | CAA01398 EAW71807 EAW71808 P21754 AK056788 AK292763 BAF85452 BC113949 AAI13950 BC140332 AAI40333 BC146482 AAI46483 BI828655 CA421411 DB328313 M60504 AAA61336 S52509 AAA13165 NM_001110354 NP_001103824 NM_007155 NP_009086 |
Function | The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
Subcellular Location | Processed zona pellucida sperm-binding protein 3: Secreted, extracellular space, extracellular matrix. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida. |
Tissue Specificity | Oocytes. |
ZP3 CRISPR/Cas9 KO Plasmid (h) - sc-402809 from Santa Cruz Biotechnology
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ZP3 HDR Plasmid (h) - sc-402809-HDR from Santa Cruz Biotechnology
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ZP3 Double Nickase Plasmid (h) - sc-402809-NIC from Santa Cruz Biotechnology
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ZP3 Double Nickase Plasmid (h2) - sc-402809-NIC-2 from Santa Cruz Biotechnology
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ZP3 CRISPR Activation Plasmid (h) - sc-402809-ACT from Santa Cruz Biotechnology
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ZP3 CRISPR Activation Plasmid (h2) - sc-402809-ACT-2 from Santa Cruz Biotechnology
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ZP3 Lentiviral Activation Particles (h) - sc-402809-LAC from Santa Cruz Biotechnology
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ZP3 Lentiviral Activation Particles (h2) - sc-402809-LAC-2 from Santa Cruz Biotechnology
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ZP3 siRNA (h) - sc-72115 from Santa Cruz Biotechnology
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ZP3 shRNA Plasmid (h) - sc-72115-SH from Santa Cruz Biotechnology
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ZP3 shRNA (h) Lentiviral Particles - sc-72115-V from Santa Cruz Biotechnology
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ZP3 RNAi - H00007784-R02 from Novus Biologicals
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MISSION® esiRNA - EHU115221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23789 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23789 from Sigma-Aldrich
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ZP3 siRNA (Human) - CRH5272 from Cohesion Biosciences
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ZP3 - MBS8219682 from MyBioSource
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shRNA set against Human Zp3 (NM_007155.5) - SHH455744 from Creative biogene
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shRNA set against Human ZP3(NM_007155.5) - SHL162620 from Creative biogene
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Human ZP3 siRNA - orb265774 from Biorbyt
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ZP3 shRNA Plasmid (Human) - CHH5272 from Cohesion Biosciences
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ZP3 miRNA 3'UTR clone - MiUTR1H-11751 from Creative biogene
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