Gene Symbol | BMP8B |
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Entrez Gene | 656 |
Alt Symbol | BMP8, OP2 |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein 8b |
Other Description | BMP-8|BMP-8B|bone morphogenetic protein 8 (osteogenic protein 2)|bone morphogenetic protein 8B|dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2))|osteogenic protein 2 |
Swissprots | Q53ZM7 E7EMY8 P34820 Q9NUF0 Q32NE5 |
Accessions | EAX07254 P34820 AB075489 AY303955 AAP74560 BC023526 BC080618 BC108678 AAI08679 BQ888513 F07575 XM_005271149 XP_005271206 XM_011542022 XP_011540324 XM_011542023 XP_011540325 XM_011542024 XP_011540326 XM_011542025 XP_011540327 XR_946748 XR_946749 XR_946750 NM_001720 NP_001711 |
Function | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | TGF-beta signaling pathway, Hippo signaling pathway |
BMP-8B CRISPR/Cas9 KO Plasmid (h) - sc-404893 from Santa Cruz Biotechnology
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BMP-8B HDR Plasmid (h) - sc-404893-HDR from Santa Cruz Biotechnology
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BMP-8B Double Nickase Plasmid (h) - sc-404893-NIC from Santa Cruz Biotechnology
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BMP-8B Double Nickase Plasmid (h2) - sc-404893-NIC-2 from Santa Cruz Biotechnology
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BMP-8B CRISPR Activation Plasmid (h) - sc-404893-ACT from Santa Cruz Biotechnology
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BMP-8B CRISPR Activation Plasmid (h2) - sc-404893-ACT-2 from Santa Cruz Biotechnology
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BMP-8B Lentiviral Activation Particles (h) - sc-404893-LAC from Santa Cruz Biotechnology
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BMP-8B Lentiviral Activation Particles (h2) - sc-404893-LAC-2 from Santa Cruz Biotechnology
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BMP-8B siRNA (h) - sc-39750 from Santa Cruz Biotechnology
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BMP-8 shRNA Plasmid (h) - sc-39750-SH from Santa Cruz Biotechnology
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BMP-8 shRNA (h) Lentiviral Particles - sc-39750-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN4008 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4008 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11308 from Sigma-Aldrich
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BMP8B siRNA (Human) - CRH0451 from Cohesion Biosciences
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BMP-8b RNAi - H00000656-R01 from Novus Biologicals
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BMP8B - MBS8240392 from MyBioSource
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shRNA set against Human BMP8B (NM_001720.3) - SHH247134 from Creative biogene
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shRNA set against Human BMP8B(NM_001720.3) - SHG102283 from Creative biogene
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Human BMP8B siRNA - orb260953 from Biorbyt
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BMP8B shRNA Plasmid (Human) - CHH0451 from Cohesion Biosciences
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BMP8B miRNA 3'UTR clone - MiUTR1H-00917 from Creative biogene
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