| Gene Symbol | ENOSF1 |
|---|---|
| Entrez Gene | 55556 |
| Alt Symbol | HSRTSBETA, RTS, TYMSAS |
| Species | Human |
| Gene Type | protein-coding |
| Description | enolase superfamily member 1 |
| Other Description | L-fuconate dehydratase|antisense RNA to thymidylate synthase|mitochondrial enolase superfamily member 1 |
| Swissprots | Q9HAS5 Q15594 Q15595 Q15407 A6NMP3 D3DUH0 B3KSL6 Q7L5Y1 B3KXE4 Q9HAS6 Q6ZS08 A8K9R5 |
| Accessions | AAG29536 AAG29537 EAX01711 EAX01712 EAX01713 EAX01714 EAX01715 Q7L5Y1 AK093873 BAG52778 AK127219 BAG54456 AK127818 BAC87148 AK292780 BAF85469 AK295850 BAG58656 AK309035 AW001055 AW082251 BC001285 AAH01285 BF591232 BG679404 BM981714 BP265528 BP271162 BQ017246 BQ028926 BQ645002 BQ710874 BX648215 X67098 CAA47471 X89602 CAA61761 XM_005258118 XP_005258175 XM_011525677 XP_011523979 XM_011525678 XP_011523980 XM_011525679 XP_011523981 XM_011525680 XP_011523982 XM_011525681 XP_011523983 XM_011525682 XP_011523984 XM_011525683 XP_011523985 XM_011525684 XP_011523986 XM_011525685 XP_011523987 XM_011525686 XP_011523988 XM_011525687 XP_011523989 XM_011525688 XP_011523990 XM_011525689 XP_011523991 XM_011525690 XP_011523992 XM_011525691 XP_011523993 XM_011525692 XP_011523994 XM_011525693 XP_011523995 XM_011525694 XP_011523996 XM_011525695 XP_011523997 XM_011525696 XP_011523998 XM_011525697 XP_011523999 XM_011525698 XP_011524000 XM_011525699 XP_011524001 XR_243810 XR_243811 XR_430041 XR_935066 XR_935067 NM_001126123 NP_001119595 NM_017512 NP_059982 NM_202758 NP_974487 |
| Function | Plays a role in the catabolism of L-fucose, a sugar that is part of the carbohydrates that are attached to cellular glycoproteins. Catalyzes the dehydration of L-fuconate to 2-keto- 3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion (PubMed:24697329). {ECO:0000269|PubMed:24697329}. |
| Subcellular Location | Mitochondrion {ECO:0000269|PubMed:16162288}. |
| Top Pathways | Fructose and mannose metabolism |
ENOSF1 CRISPR/Cas9 KO Plasmid (h) - sc-412546 from Santa Cruz Biotechnology
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ENOSF1 HDR Plasmid (h) - sc-412546-HDR from Santa Cruz Biotechnology
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ENOSF1 Double Nickase Plasmid (h) - sc-412546-NIC from Santa Cruz Biotechnology
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ENOSF1 Double Nickase Plasmid (h2) - sc-412546-NIC-2 from Santa Cruz Biotechnology
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ENOSF1 CRISPR Activation Plasmid (h) - sc-412546-ACT from Santa Cruz Biotechnology
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ENOSF1 CRISPR Activation Plasmid (h2) - sc-412546-ACT-2 from Santa Cruz Biotechnology
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ENOSF1 Lentiviral Activation Particles (h) - sc-412546-LAC from Santa Cruz Biotechnology
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ENOSF1 Lentiviral Activation Particles (h2) - sc-412546-LAC-2 from Santa Cruz Biotechnology
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ENOSF1 siRNA (h) - sc-77275 from Santa Cruz Biotechnology
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ENOSF1 shRNA Plasmid (h) - sc-77275-SH from Santa Cruz Biotechnology
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ENOSF1 shRNA (h) Lentiviral Particles - sc-77275-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU088081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7876 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7876 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03369 from Sigma-Aldrich
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ENOSF1 siRNA (Human) - CRJ0738 from Cohesion Biosciences
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ENOSF1 - MBS8210646 from MyBioSource
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shRNA set against Human ENOSF1 (NM_017512.5) - SHH285873 from Creative biogene
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Human ENOSF1 siRNA - orb271239 from Biorbyt
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ENOSF1 shRNA Plasmid (Human) - CHJ0738 from Cohesion Biosciences
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ENOSF1 miRNA 3'UTR clone - MiUTR3H-09215 from Creative biogene
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ENOSF1 miRNA 3'UTR clone - MiUTR3H-09216 from Creative biogene
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ENOSF1 miRNA 3'UTR clone - MiUTR3H-09217 from Creative biogene
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