Gene Symbol | FOLR3 |
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Entrez Gene | 2352 |
Alt Symbol | FR-G, FR-gamma, gamma-hFR |
Species | Human |
Gene Type | protein-coding |
Description | folate receptor 3 (gamma) |
Other Description | folate receptor gamma |
Swissprots | P41439 Q05C14 J3KQ90 |
Accessions | AAC98303 EAW74843 EAW74844 EAW74845 P41439 BC030285 AAH30285 BC126398 BC141505 AAI41506 BC148785 AAI48786 U08470 AAA18381 U08471 AAA18382 Z32564 CAA83553 Z32633 CAA83566 XM_011544873 XP_011543175 XM_011544874 XP_011543176 XM_011544875 XP_011543177 XM_011544876 XP_011543178 NM_000804 NP_000795 |
Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate. |
Subcellular Location | Secreted. |
Tissue Specificity | Spleen, thymus, bone marrow, ovarian carcinoma, and uterine carcinoma. |
Top Pathways | Endocytosis |
γ-FR CRISPR/Cas9 KO Plasmid (h) - sc-403347 from Santa Cruz Biotechnology
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γ-FR HDR Plasmid (h) - sc-403347-HDR from Santa Cruz Biotechnology
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γ-FR Double Nickase Plasmid (h) - sc-403347-NIC from Santa Cruz Biotechnology
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γ-FR Double Nickase Plasmid (h2) - sc-403347-NIC-2 from Santa Cruz Biotechnology
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γ-FR CRISPR Activation Plasmid (h) - sc-403347-ACT from Santa Cruz Biotechnology
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γ-FR CRISPR Activation Plasmid (h2) - sc-403347-ACT-2 from Santa Cruz Biotechnology
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γ-FR Lentiviral Activation Particles (h) - sc-403347-LAC from Santa Cruz Biotechnology
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γ-FR Lentiviral Activation Particles (h2) - sc-403347-LAC-2 from Santa Cruz Biotechnology
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γ-FR siRNA (h) - sc-39975 from Santa Cruz Biotechnology
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γ-FR shRNA Plasmid (h) - sc-39975-SH from Santa Cruz Biotechnology
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γ-FR shRNA (h) Lentiviral Particles - sc-39975-V from Santa Cruz Biotechnology
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FOLR3 RNAi - H00002352-R02 from Novus Biologicals
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MISSION® esiRNA - EHU043641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8869 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8869 from Sigma-Aldrich
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FOLR3 siRNA (Human) - CRH1643 from Cohesion Biosciences
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FOLR3 - MBS8237813 from MyBioSource
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shRNA set against Human FOLR3(NM_000804.2) - SHH065387 from Creative biogene
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FOLR3 shRNA Plasmid (Human) - CHH1643 from Cohesion Biosciences
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FOLR3 miRNA 3'UTR clone - MiUTR1H-03804 from Creative biogene
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