| Gene Symbol |
CYP19A1
|
| Entrez Gene |
1588
|
| Alt Symbol |
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 19, subfamily A, polypeptide 1
|
| Other Description |
aromatase|cytochrome P-450AROM|cytochrome P450 19A1|cytochrome P450, subfamily XIX (aromatization of androgens)|estrogen synthase|estrogen synthetase|flavoprotein-linked monooxygenase|microsomal monooxygenase
|
| Swissprots |
Q58FA0 Q3B764 Q16731 P11511 Q8IYJ7
|
| Accessions |
AAA35728 AAB21520 AAD14894 AAX44046 EAW77413 EAW77414 EAW77415 EAW77416 P11511 AK291778 BAF84467 AM392533 CAL37411 AM393184 CAL38062 BC020767 AAH20767 BC022896 AAH22896 BC035714 AAH35714 BC035959 AAH35959 BC056258 AAH56258 BC107785 AAI07786 BG621764 BQ024157 DA853862 DQ118405 AAZ23558 J04127 AAA52132 M18856 AAA35556 M22246 AAA35557 M28420 AAA52141 S52789 S52793 S58866 AAB26390 S85075 AAB21500 X13589 CAA31929 Y07508 CAA68807 XM_005254190 XP_005254247 XM_005254191 XP_005254248 NM_000103 NP_000094 NM_031226 NP_112503
|
| Function |
Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
|
| Subcellular Location |
Membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Brain, placenta and gonads. {ECO:0000269|PubMed:2040633, ECO:0000269|PubMed:3018730, ECO:0000269|PubMed:7690033, ECO:0000269|PubMed:8117272}.
|
| Top Pathways |
Steroid hormone biosynthesis, Ovarian steroidogenesis
|