Gene Symbol | ABCC8 |
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Entrez Gene | 6833 |
Alt Symbol | ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, SUR1delta2, TNDM2 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
Other Description | ATP-binding cassette sub-family C member 8|ATP-binding cassette transporter sub-family C member 8|sulfonylurea receptor (hyperinsulinemia)|sulfonylurea receptor 1 |
Swissprots | Q09428 Q16583 E3UYX6 O75948 A6NMX8 |
Accessions | AAB02417 AAB02418 AAB36700 EAW68436 EAW68437 Q09428 AB209084 BAD92321 AF087138 AAC36724 AK297560 BAH12616 AW444836 BC167829 AAI67829 BM313666 BM352492 BU950000 DB636549 HM635782 ADM67556 L40625 AAA99227 L78207 AAB02278 R84665 U63421 AAB36699 XM_011520331 XP_011518633 XM_011520332 XP_011518634 XM_011520333 XP_011518635 XM_011520334 XP_011518636 XR_930890 XR_930891 XR_930892 XR_930893 NM_000352 NP_000343 NM_001287174 NP_001274103 |
Function | Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | ABC transporters, Type II diabetes mellitus |
SUR1 CRISPR/Cas9 KO Plasmid (h) - sc-401540 from Santa Cruz Biotechnology
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SUR1 HDR Plasmid (h) - sc-401540-HDR from Santa Cruz Biotechnology
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SUR1 Double Nickase Plasmid (h) - sc-401540-NIC from Santa Cruz Biotechnology
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SUR1 Double Nickase Plasmid (h2) - sc-401540-NIC-2 from Santa Cruz Biotechnology
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SUR1 CRISPR Activation Plasmid (h) - sc-401540-ACT from Santa Cruz Biotechnology
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SUR1 CRISPR Activation Plasmid (h2) - sc-401540-ACT-2 from Santa Cruz Biotechnology
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SUR1 Lentiviral Activation Particles (h) - sc-401540-LAC from Santa Cruz Biotechnology
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SUR1 Lentiviral Activation Particles (h2) - sc-401540-LAC-2 from Santa Cruz Biotechnology
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SUR-1 siRNA (h) - sc-42634 from Santa Cruz Biotechnology
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SUR-1 shRNA Plasmid (h) - sc-42634-SH from Santa Cruz Biotechnology
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SUR-1 shRNA (h) Lentiviral Particles - sc-42634-V from Santa Cruz Biotechnology
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SUR-1/2 siRNA (h) - sc-44131 from Santa Cruz Biotechnology
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SUR-1/2 shRNA Plasmid (h) - sc-44131-SH from Santa Cruz Biotechnology
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SUR-1/2 shRNA (h) Lentiviral Particles - sc-44131-V from Santa Cruz Biotechnology
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SUR1 RNAi - H00006833-R02 from Novus Biologicals
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MISSION® esiRNA - EHU024291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1689 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1689 from Sigma-Aldrich
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ABCC8 siRNA (Human) - CRH4671 from Cohesion Biosciences
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ABCC8 - MBS8205897 from MyBioSource
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shRNA set against Human ABCC8 (NM_000352.3) - SHH229174 from Creative biogene
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shRNA set against Human ABCC8(NM_000352.3) - SHG024373 from Creative biogene
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Human ABCC8 siRNA - orb265173 from Biorbyt
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ABCC8 shRNA Plasmid (Human) - CHH4671 from Cohesion Biosciences
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ABCC8 miRNA 3'UTR clone - MiUTR1H-00043 from Creative biogene
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