Gene Symbol | DENND6B |
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Entrez Gene | 414918 |
Alt Symbol | AFI1B, FAM116B |
Species | Human |
Gene Type | protein-coding |
Description | DENN/MADD domain containing 6B |
Other Description | DENN domain-containing protein 6B|family with sequence similarity 116, member B|protein DENND6B|protein FAM116B |
Swissprots | Q8NEG7 A6X8I5 |
Accessions | CAO03304 CAO03484 CAO03524 CAO03525 CAO03578 CAO03579 CAO03620 CAO03621 EAW73528 EAW73529 Q8NEG7 AA864612 AK054743 BC031069 AAH31069 BI758775 BM981037 BX363595 XM_005261914 XP_005261971 XM_011530692 XP_011528994 XM_011530693 XP_011528995 XM_011530694 XP_011528996 XM_011530695 XP_011528997 XR_430477 XR_430478 NM_001001794 NP_001001794 |
Function | Guanine nucleotide exchange factor (GEF) for RAB14. Also has some, lesser GEF activity towards RAB35. {ECO:0000269|PubMed:22595670}. |
Subcellular Location | Recycling endosome {ECO:0000305}. Cytoplasm {ECO:0000305}. |
MISSION® esiRNA - EHU102521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8135 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8135 from Sigma-Aldrich
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DENND6B siRNA (Human) - CRJ8214 from Cohesion Biosciences
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DENND6B - MBS8206387 from MyBioSource
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DENND6B siRNA (h) - sc-77305 from Santa Cruz Biotechnology
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DENND6B shRNA Plasmid (h) - sc-77305-SH from Santa Cruz Biotechnology
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DENND6B shRNA (h) Lentiviral Particles - sc-77305-V from Santa Cruz Biotechnology
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shRNA set against Human FAM116B (NM_001001794.3) - SHH289225 from Creative biogene
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Human DENND6B siRNA - orb278715 from Biorbyt
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DENND6B shRNA Plasmid (Human) - CHJ8214 from Cohesion Biosciences
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DENND6B miRNA 3'UTR clone - MiUTR3H-14810 from Creative biogene
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