| Gene Symbol |
SP7
|
| Entrez Gene |
121340
|
| Alt Symbol |
OI11, OI12, OSX, osterix
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Sp7 transcription factor
|
| Other Description |
transcription factor Sp7|zinc finger protein osterix
|
| Swissprots |
Q8TDD2 Q3MJ72 B3KY26 Q7Z718
|
| Accessions |
EAW96695 EAW96696 EAW96697 Q8TDD2 AF466179 AAO33377 AF477981 AAL84281 AK128520 BAG54688 AY150673 AAN85556 AY150674 AAN85557 BC101549 AAI01550 BC113613 AAI13614 EU446563 ABZ92092 HY020346 XM_011537900 XP_011536202 XM_011537901 XP_011536203 NM_001173467 NP_001166938 NM_001300837 NP_001287766 NM_152860 NP_690599
|
| Function |
Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Tissue Specificity |
Restricted to bone-derived cell. {ECO:0000269|PubMed:15474293}.
|