| Gene Symbol |
CENPV
|
| Entrez Gene |
201161
|
| Alt Symbol |
3110013H01Rik, CENP-V, PRR6, p30
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centromere protein V
|
| Other Description |
nuclear protein p30|proline rich 6|proline-rich protein 6
|
| Swissprots |
Q8NFH6 Q3L8N5 B2RPK2 Q7Z7K6
|
| Accessions |
EAX04499 EAX04500 Q7Z7K6 AF514992 AAM76703 AY382899 AAR24368 BC052604 AAH52604 BC137486 AAI37487 BC137487 AAI37488 BQ052702 BU618545 NM_181716 NP_859067
|
| Function |
Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis. {ECO:0000269|PubMed:18772885}.
|
| Subcellular Location |
Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Enriched at the nuclear periphery and around the nucleolus. In mitotic cells, localizes to kinetochores from prometaphase to metaphase. At anaphase onset, transfers to the spindle midzone and then to the mid-body in telophase and cytokinesis.
|