Gene Symbol | NOL9 |
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Entrez Gene | 79707 |
Alt Symbol | Grc3, NET6 |
Species | Human |
Gene Type | protein-coding |
Description | nucleolar protein 9 |
Other Description | polynucleotide 5'-hydroxyl-kinase NOL9|polynucleotide 5'-kinase |
Swissprots | Q7L4D6 Q5SY16 Q2NL84 Q96EE0 Q4VBY3 Q9H5L4 Q6P472 |
Accessions | EAW71550 Q5SY16 AK026976 BAB15611 AK091284 AK289653 BAF82342 BC009257 AAH09257 BC012439 AAH12439 BC063639 AAH63639 BC073860 BC094836 AAH94836 BC105095 AAI05096 BC110849 AAI10850 BC112278 AAI12279 BC143646 BE383415 BF969522 BI828678 BU728251 BX393201 CA391953 CA432392 HQ258631 ADR83383 XM_005263493 XP_005263550 XM_011542146 XP_011540448 XM_011542147 XP_011540449 NM_024654 NP_078930 |
Function | Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA. {ECO:0000269|PubMed:21063389}. |
Subcellular Location | Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:21063389}. Note=Colocalizes with pre-60S rRNP particles. |
NOL9 CRISPR/Cas9 KO Plasmid (h) - sc-410127 from Santa Cruz Biotechnology
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NOL9 HDR Plasmid (h) - sc-410127-HDR from Santa Cruz Biotechnology
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NOL9 Double Nickase Plasmid (h) - sc-410127-NIC from Santa Cruz Biotechnology
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NOL9 Double Nickase Plasmid (h2) - sc-410127-NIC-2 from Santa Cruz Biotechnology
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NOL9 CRISPR Activation Plasmid (h) - sc-410127-ACT from Santa Cruz Biotechnology
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NOL9 CRISPR Activation Plasmid (h2) - sc-410127-ACT-2 from Santa Cruz Biotechnology
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NOL9 Lentiviral Activation Particles (h) - sc-410127-LAC from Santa Cruz Biotechnology
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NOL9 Lentiviral Activation Particles (h2) - sc-410127-LAC-2 from Santa Cruz Biotechnology
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NOL9 siRNA (h) - sc-88187 from Santa Cruz Biotechnology
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NOL9 shRNA Plasmid (h) - sc-88187-SH from Santa Cruz Biotechnology
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NOL9 shRNA (h) Lentiviral Particles - sc-88187-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU017351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15404 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15404 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06242 from Sigma-Aldrich
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NOL9 siRNA (Human) - CRJ2502 from Cohesion Biosciences
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shRNA set against Human NOL9 (NM_024654.4) - SHH353596 from Creative biogene
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NOL9 shRNA Plasmid (Human) - CHJ2502 from Cohesion Biosciences
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NOL9 miRNA 3'UTR clone - MiUTR4H-TG06067 from Creative biogene
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