DCTN1

Gene Symbol	DCTN1
Entrez Gene	1639
Alt Symbol	DAP-150, DP-150, P135
Species	Human
Gene Type	protein-coding
Description	dynactin 1
Other Description	150 kDa dynein-associated polypeptide|dynactin 1 (p150, glued homolog, Drosophila)|dynactin subunit 1
Swissprots	E9PGE1 O95296 Q9UIU2 G5E9H4 Q9UIU1 E9PFS5 B4DM45 A8MY36 Q9BRM9 Q14203 Q6IQ37
Accessions	AAD03694 AAD55811 AAD55812 CCQ43248 EAW99684 EAW99685 EAW99686 EAW99687 Q14203 AB209625 BAD92862 AJ709213 AK055298 AK297286 BAG59757 AK314352 AK315014 BC006163 BC013978 BC071583 AAH71583 BT006758 AAP35404 BX640799 CAE45882 BX647925 CAH10575 BX647972 CAH10572 CA448857 DA111497 DA315227 DA417935 DC309469 EU831597 ACE87197 EU831684 ACE86518 U73799 AAB52575 U90445 AAD00701 X98801 CAA67333 NM_001135040 NP_001128512 NM_001135041 NP_001128513 NM_001190836 NP_001177765 NM_001190837 NP_001177766 NM_004082 NP_004073 NM_023019 NP_075408 NR_033935
Function	Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17828277}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17828277}. Note=Colocalizes with microtubules.
Tissue Specificity	Brain.
Top Pathways	Huntington's disease, Vasopressin-regulated water reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DCTN1 peptide - ab23214 from Abcam Category Peptide Species Human

Human DCTN1 protein fragment - ab132084 from Abcam Category Protein Source Wheat germ Species Human

DCTN1 / Dynactin 1 Antibody Blocking Peptide - LS-E25430 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DCTN1 / Dynactin 1 Antibody Blocking Peptide - LS-E18669 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Dynactin Subunit 1/DCTN1 Protein - H00001639-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DCTN1 blocking peptide - GTX11806-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

DCTN1 Peptide - AC21-0258-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Dynactin subunit 1 - H00001639-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Dynactin subunit 1 - H00001639-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Dynactin Peptide - 45-508P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

Recombinant Human DCTN1, His-tagged - DCTN1-27132TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Dynactin subunit 1(DCTN1) ,partial - CSB-YP619866HU CSB-EP619866HU CSB-BP619866HU CSB-MP619866HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Dynactin, Peptide - MBS425873 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

Dynactin Subunit 1/DCTN1 Recombinant Protein Antigen - NBP2-33976PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DCTN1-Antibody-N-term-Blocking-Peptide - BP9706a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DCTN1 Peptide, Human - M34GP04099H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human DCTN1 protein - orb10266 from Biorbyt Category Protein Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

Dynactin subunit 1 (DCTN1), partial, Recombinant Protein - MBS1457410 from MyBioSource Category Protein Prices $1,130.00, $1,130.00, $1,360.00, $1,360.00, $1,745.00, $1,745.00, $2,205.00, $2,205.00, $2,240.00, $3,450.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

DCTN1 Recombinant Protein (Human) (OPCA04679) - OPCA04679 from Aviva Systems Biology Category Protein Species Human

DCTN1 Immunizing peptide - orb17717 from Biorbyt Category Peptide

Recombinant Human DCTN1 Protein, His-SUMO-tagged - DCTN1-1184H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human DCTN1 Protein, GST-tagged - DCTN1-2410H from Creative Biomart Category Protein Source Wheat Germ Species Human

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