| Gene Symbol |
MICALL1
|
| Entrez Gene |
85377
|
| Alt Symbol |
MICAL-L1, MIRAB13
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MICAL-like 1
|
| Other Description |
MICAL-like protein 1|molecule interacting with Rab13
|
| Swissprots |
Q9UH44 Q9BY92 Q9UH43 Q8N3N8 Q9BVL9 Q7RTP5 Q9UH45 Q8N3F8 Q5TI16
|
| Accessions |
EAW60199 Q8N3F8 AB051455 BAB33338 AJ496196 CAD42713 AK056603 AK127819 AL833860 CAD38718 AL834373 CAD39036 BC001090 AAH01090 BC082243 AAH82243 BC142605 AAI42606 BC143050 AAI43051 BC146383 AAI46384 BC148804 AAI48805 BK000466 DAA01345 CA307559 CA432878 CB997694 CR456437 CAG30323 CR749566 CAH18362 DB476014 DR004306 XM_005261791 XP_005261848 XM_005261792 XP_005261849 XM_011530471 XP_011528773 XM_011530472 XP_011528774 XM_011530473 XP_011528775 XM_011530474 XP_011528776 XM_011530475 XP_011528777 XM_011530476 XP_011528778 XR_937943 NM_033386 NP_203744
|
| Function |
Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth. {ECO:0000269|PubMed:19864458, ECO:0000269|PubMed:20801876, ECO:0000269|PubMed:21795389, ECO:0000269|PubMed:23596323}.
|
| Subcellular Location |
Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane. Note=Localization to late endosomes is actin-dependent. Association to tubular recycling endosomes is regulated by RAB35 and ARF6.
|