Gene Symbol |
HSD17B3
|
Entrez Gene |
3293
|
Alt Symbol |
EDH17B3, SDR12C2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
hydroxysteroid (17-beta) dehydrogenase 3
|
Other Description |
17-beta-HSD 3|17-beta-HSD3|17-beta-hydroxysteroid dehydrogenase type 3|short chain dehydrogenase/reductase family 12C member 2|short chain dehydrogenase/reductase family 12C, member 2|testicular 17-beta-hydroxysteroid dehydrogenase|testosterone 17-beta-dehydrogenase 3
|
Swissprots |
P37058 Q5U0Q6
|
Accessions |
AAP88937 CBH19319 EAW92645 P37058 BC034281 AAH34281 BT019371 AAV38178 CR541894 CAG46692 DQ891812 ABM82738 DQ894995 ABM85921 U05659 AAC50066 XM_005251970 XP_005252027 XM_006717095 XP_006717158 XM_011518618 XP_011516920 XM_011518619 XP_011516921 XM_011518620 XP_011516922 XM_011518621 XP_011516923 NM_000197 NP_000188
|
Function |
Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
|
Tissue Specificity |
Testis.
|
Top Pathways |
Steroid hormone biosynthesis
|