Gene Symbol | HSD17B3 |
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Entrez Gene | 3293 |
Alt Symbol | EDH17B3, SDR12C2 |
Species | Human |
Gene Type | protein-coding |
Description | hydroxysteroid (17-beta) dehydrogenase 3 |
Other Description | 17-beta-HSD 3|17-beta-HSD3|17-beta-hydroxysteroid dehydrogenase type 3|short chain dehydrogenase/reductase family 12C member 2|short chain dehydrogenase/reductase family 12C, member 2|testicular 17-beta-hydroxysteroid dehydrogenase|testosterone 17-beta-dehydrogenase 3 |
Swissprots | P37058 Q5U0Q6 |
Accessions | AAP88937 CBH19319 EAW92645 P37058 BC034281 AAH34281 BT019371 AAV38178 CR541894 CAG46692 DQ891812 ABM82738 DQ894995 ABM85921 U05659 AAC50066 XM_005251970 XP_005252027 XM_006717095 XP_006717158 XM_011518618 XP_011516920 XM_011518619 XP_011516921 XM_011518620 XP_011516922 XM_011518621 XP_011516923 NM_000197 NP_000188 |
Function | Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. |
Tissue Specificity | Testis. |
Top Pathways | Steroid hormone biosynthesis |
17β-HSD3 siRNA (h) - sc-61916 from Santa Cruz Biotechnology
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17β-HSD3 shRNA Plasmid (h) - sc-61916-SH from Santa Cruz Biotechnology
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17β-HSD3 shRNA (h) Lentiviral Particles - sc-61916-V from Santa Cruz Biotechnology
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HSD17B3 RNAi - H00003293-R01 from Novus Biologicals
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MISSION® esiRNA - EHU037511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1647 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1647 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00303 from Sigma-Aldrich
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HSD17B3 siRNA (Human) - CRH2250 from Cohesion Biosciences
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HSD17B3 - MBS8224270 from MyBioSource
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shRNA set against Human HSD17B3(NM_000197.1) - SHH132713 from Creative biogene
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HSD17B3 shRNA Plasmid (Human) - CHH2250 from Cohesion Biosciences
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HSD17B3 miRNA 3'UTR clone - MiUTR1H-04717 from Creative biogene
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