Gene Symbol | CAMKMT |
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Entrez Gene | 79823 |
Alt Symbol | C2orf34, CLNMT, CaM KMT, Cam, KMT |
Species | Human |
Gene Type | protein-coding |
Description | calmodulin-lysine N-methyltransferase |
Other Description | - |
Swissprots | Q9H5G8 Q8N6P5 Q4ZG15 Q7Z624 Q53SS6 |
Accessions | AAX88866 AAX93163 EAX00272 EAX00273 EAX00274 Q7Z624 AI933944 AK027104 BAB15658 BC022192 BC029359 AAH29359 BC053733 AAH53733 DA760277 DB461740 HQ447588 ADQ32074 XM_005264567 XP_005264624 XM_011533111 XP_011531413 XM_011533112 XP_011531414 XM_011533113 XP_011531415 XR_939721 XR_939722 XR_939723 NM_024766 NP_079042 |
Function | Catalyzes the trimethylation of 'Lys-116' in calmodulin. {ECO:0000269|PubMed:20975703}. |
Subcellular Location | Isoform 1: Cytoplasm. Nucleus. |
Tissue Specificity | Isoform 1 is expressed in brain,liver, muscle colon and lung. Isoform 2 is expressed in colon, testis, kidney and brain. Isoform 1 and isoform 2 are expressed in normal lymphoblastoid cells but not in lymphoblastoid cells from patients with hypotonia-cystinuria syndrome. {ECO:0000269|PubMed:15913950}. |
Top Pathways | Lysine degradation |
C2orf34 CRISPR/Cas9 KO Plasmid (h) - sc-413257 from Santa Cruz Biotechnology
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C2orf34 HDR Plasmid (h) - sc-413257-HDR from Santa Cruz Biotechnology
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C2orf34 Double Nickase Plasmid (h) - sc-413257-NIC from Santa Cruz Biotechnology
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C2orf34 Double Nickase Plasmid (h2) - sc-413257-NIC-2 from Santa Cruz Biotechnology
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C2orf34 CRISPR Activation Plasmid (h) - sc-413257-ACT from Santa Cruz Biotechnology
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C2orf34 CRISPR Activation Plasmid (h2) - sc-413257-ACT-2 from Santa Cruz Biotechnology
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C2orf34 Lentiviral Activation Particles (h) - sc-413257-LAC from Santa Cruz Biotechnology
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C2orf34 Lentiviral Activation Particles (h2) - sc-413257-LAC-2 from Santa Cruz Biotechnology
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C2orf34 siRNA (h) - sc-94666 from Santa Cruz Biotechnology
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C2orf34 shRNA Plasmid (h) - sc-94666-SH from Santa Cruz Biotechnology
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C2orf34 shRNA (h) Lentiviral Particles - sc-94666-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU034011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4823 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4823 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04572 from Sigma-Aldrich
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CAMKMT siRNA (Human) - CRJ2591 from Cohesion Biosciences
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CAMKMT - MBS8201725 from MyBioSource
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shRNA set against Human CAMKMT (NM_024766.4) - SHH254093 from Creative biogene
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Human CAMKMT siRNA - orb273092 from Biorbyt
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CAMKMT shRNA Plasmid (Human) - CHJ2591 from Cohesion Biosciences
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CAMKMT miRNA 3'UTR clone - MiUTR3H-10685 from Creative biogene
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