PLEKHM1

Gene Symbol PLEKHM1
Entrez Gene 9842
Alt Symbol AP162, B2, OPTB6
Species Human
Gene Type protein-coding
Description pleckstrin homology domain containing, family M (with RUN domain) member 1
Other Description 162 kDa adapter protein|PH domain-containing family M member 1|pleckstrin homology domain-containing family M member 1
Swissprots Q9NPP5 Q6P2R5 Q9NYA0 Q8TEL9 Q9Y4G2
Accessions EAW51526 Q9Y4G2 AB002354 BAA20813 AJ002220 CAB91652 AK025379 AK074103 BAB84929 AK299116 BAG61171 AK299467 BAG61433 AL389948 CAB97526 BC053848 BC064361 AAH64361 DB064851 X85792 CAA59791 XM_006722201 XP_006722264 XM_006722202 XP_006722265 XM_006725277 XP_006725340 XM_006725278 XP_006725341 XM_006725632 XP_006725695 XM_006725633 XP_006725696 XM_011525523 XP_011523825 XM_011525524 XP_011523826 XM_011525525 XP_011523827 XM_011525526 XP_011523828 XM_011525527 XP_011523829 XM_011525528 XP_011523830 XM_011546359 XP_011544661 XM_011546360 XP_011544662 XM_011546361 XP_011544663 XM_011546362 XP_011544664 XM_011546363 XP_011544665 XM_011547496 XP_011545798 XM_011547497 XP_011545799 XM_011547498 XP_011545800 XM_011547499 XP_011545801 XM_011547500 XP_011545802 XM_011547501 XP_011545803 XR_934624 XR_934625 XR_951534 XR_951535 XR_952488 XR_952489 NM_014798 NP_055613 NR_027774 NR_027782
Function Involved in vesicular transport in the osteoclast (By similarity). May have a role in sialyl-lex-mediated transduction of apoptotic signals. {ECO:0000250, ECO:0000269|PubMed:12820725}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Expressed in placenta, liver, prostate, thymus, spleen, ovary, colon, colon carcinoma and peripheral blood lymphocytes (PBL). Weakly expressed in brain, lung, kidney, and testis. No expression in heart, skeletal muscle, pancreas and small intestine. Predominantly expressed in the breast carcinoma cell line MCF-7. {ECO:0000269|PubMed:12820725, ECO:0000269|PubMed:9205841}.

PLEKHM1 CRISPR/Cas9 KO Plasmid (h) - sc-411361 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 HDR Plasmid (h) - sc-411361-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 Double Nickase Plasmid (h) - sc-411361-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 Double Nickase Plasmid (h2) - sc-411361-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 CRISPR Activation Plasmid (h) - sc-411361-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 CRISPR Activation Plasmid (h2) - sc-411361-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 Lentiviral Activation Particles (h) - sc-411361-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 Lentiviral Activation Particles (h2) - sc-411361-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLEKHM1 siRNA (h) - sc-93882 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLEKHM1 shRNA Plasmid (h) - sc-93882-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLEKHM1 shRNA (h) Lentiviral Particles - sc-93882-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLEKHM1 RNAi - H00009842-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU109831 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU115761 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16971 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16971 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10759 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10759

PLEKHM1 siRNA (Human) - CRH6594 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLEKHM1 RNAi - H00009842-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PLEKHM1 (NM_014798.2) - SHH377728 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLEKHM1 siRNA - orb267096 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLEKHM1 shRNA Plasmid (Human) - CHH6594 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLEKHM1 miRNA 3'UTR clone - MiUTR3H-11911 from Creative biogene

Species Reactivities Human
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