Gene Symbol |
MIS12
|
Entrez Gene |
79003
|
Alt Symbol |
2510025F08Rik, KNTC2AP, MTW1, hMis12
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
MIS12 kinetochore complex component
|
Other Description |
MIS12 homolog|MIS12, MIND kinetochore complex component, homolog|homolog of yeast Mis12|protein MIS12 homolog
|
Swissprots |
Q96N24 Q9H081
|
Accessions |
EAW90328 Q9H081 AK056072 AK289939 BAF82628 AL136906 CAB66840 AM392972 CAL37850 AM393558 CAL38435 BC000229 AAH00229 CR533460 CAG38491 DA182670 DA964146 DB258115 XM_005256797 XP_005256854 XM_005256798 XP_005256855 NM_001258217 NP_001245146 NM_001258218 NP_001245147 NM_001258219 NP_001245148 NM_001258220 NP_001245149 NM_024039 NP_076944
|
Function |
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. {ECO:0000269|PubMed:12515822, ECO:0000269|PubMed:15502821, ECO:0000269|PubMed:16585270}.
|
Subcellular Location |
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
|