Gene Symbol | PRPF18 |
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Entrez Gene | 8559 |
Alt Symbol | PRP18, hPrp18 |
Species | Human |
Gene Type | protein-coding |
Description | pre-mRNA processing factor 18 |
Other Description | PRP18 homolog|PRP18 pre-mRNA processing factor 18 homolog|PRP18 pre-mRNA processing factor 18 homolog(PRPF18)|pre-mRNA-splicing factor 18 |
Swissprots | Q5T9P9 Q9BUI9 Q99633 |
Accessions | CCQ43229 EAW86280 EAW86281 EAW86282 EAW86283 Q99633 AF087997 AI580379 AK314814 BAG37337 AU142253 BC000794 AAH00794 BC002572 U51990 AAB41490 XM_005252634 XP_005252691 XM_005252636 XP_005252693 XM_011519753 XP_011518055 XM_011519754 XP_011518056 NM_003675 NP_003666 |
Function | Participates in the second step of pre-mRNA splicing. {ECO:0000269|PubMed:9000057}. |
Subcellular Location | Nucleus speckle {ECO:0000250}. Note=Colocalizes with spliceosomal snRNPs. {ECO:0000250}. |
Top Pathways | Spliceosome |
PRPF18 CRISPR/Cas9 KO Plasmid (h) - sc-407741 from Santa Cruz Biotechnology
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PRPF18 HDR Plasmid (h) - sc-407741-HDR from Santa Cruz Biotechnology
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PRPF18 Double Nickase Plasmid (h) - sc-407741-NIC from Santa Cruz Biotechnology
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PRPF18 Double Nickase Plasmid (h2) - sc-407741-NIC-2 from Santa Cruz Biotechnology
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PRPF18 CRISPR Activation Plasmid (h) - sc-407741-ACT from Santa Cruz Biotechnology
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PRPF18 CRISPR Activation Plasmid (h2) - sc-407741-ACT-2 from Santa Cruz Biotechnology
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PRPF18 Lentiviral Activation Particles (h) - sc-407741-LAC from Santa Cruz Biotechnology
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PRPF18 Lentiviral Activation Particles (h2) - sc-407741-LAC-2 from Santa Cruz Biotechnology
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PRPF18 siRNA (h) - sc-90497 from Santa Cruz Biotechnology
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PRPF18 shRNA Plasmid (h) - sc-90497-SH from Santa Cruz Biotechnology
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PRPF18 shRNA (h) Lentiviral Particles - sc-90497-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU094231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17470 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17470 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04016 from Sigma-Aldrich
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PRPF18 siRNA (Human) - CRH5628 from Cohesion Biosciences
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shRNA set against Human PRPF18 (NM_003675.3) - SHH383692 from Creative biogene
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shRNA set against Human PRPF18(NM_003675.3) - SHR142746 from Creative biogene
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Human PRPF18 siRNA - orb266130 from Biorbyt
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PRPF18 shRNA Plasmid (Human) - CHH5628 from Cohesion Biosciences
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PRPF18 miRNA 3'UTR clone - MiUTR1H-08312 from Creative biogene
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