| Gene Symbol |
ECEL1
|
| Entrez Gene |
9427
|
| Alt Symbol |
DA5D, DINE, ECEX, XCE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
endothelin converting enzyme-like 1
|
| Other Description |
X converting enzyme|damage induced neuronal endopeptidase|endothelin-converting enzyme-like 1
|
| Swissprots |
Q53RF9 O95672 Q86TH4 Q6UW86 Q45UD9 Q9NY95
|
| Accessions |
AAY24101 CAB86601 EAW70999 EAW71000 O95672 AB030579 BAC66225 AB073895 AY358923 AAQ89282 BC050453 AAH50453 BM564570 DQ114476 AAZ22338 Y16187 CAA76113 NM_001290787 NP_001277716 NM_004826 NP_004817
|
| Function |
May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in the CNS, in particular in putamen, spinal cord, medulla and subthalamic nucleus. A strong signal was also detected in uterine subepithelial cells and around renal blood vessels. Detected at lower levels in amygdala, caudate, thalamus, pancreas and skeletal muscle. Detected at very low levels in substantia nigra, cerebellum, cortex, corpus callosum and hippocampus.
|