Gene Symbol | Polm |
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Entrez Gene | 54125 |
Alt Symbol | AI462166, B230309I03Rik, Tdt-N |
Species | Mouse |
Gene Type | protein-coding |
Description | polymerase (DNA directed), mu |
Other Description | DNA polymerase mu|DNA-directed DNA polymerase mu|DNA-directed DNA/RNA polymerase mu|pol Mu|terminal transferase |
Swissprots | Q9JIW4 Q9JJW9 G5E840 |
Accessions | CAC38040 EDL40560 EDL40561 Q9JIW4 AF176098 AAF27552 AJ251804 CAB71154 AK137747 AK179467 AK183362 AK189181 AK203359 AK208265 AK210858 BC056213 AAH56213 BC056996 CJ130894 XM_006514758 XP_006514821 XM_006514759 XP_006514822 NM_017401 NP_059097 |
Function | Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. {ECO:0000269|PubMed:16860755, ECO:0000269|PubMed:17483519}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Non-homologous end-joining |
DNA pol μ CRISPR/Cas9 KO Plasmid (m) - sc-424787 from Santa Cruz Biotechnology
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DNA pol μ HDR Plasmid (m) - sc-424787-HDR from Santa Cruz Biotechnology
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DNA pol μ Double Nickase Plasmid (m) - sc-424787-NIC from Santa Cruz Biotechnology
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DNA pol μ Double Nickase Plasmid (m2) - sc-424787-NIC-2 from Santa Cruz Biotechnology
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DNA pol μ CRISPR Activation Plasmid (m) - sc-424787-ACT from Santa Cruz Biotechnology
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DNA pol μ CRISPR Activation Plasmid (m2) - sc-424787-ACT-2 from Santa Cruz Biotechnology
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DNA pol μ Lentiviral Activation Particles (m) - sc-424787-LAC from Santa Cruz Biotechnology
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DNA pol μ Lentiviral Activation Particles (m2) - sc-424787-LAC-2 from Santa Cruz Biotechnology
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DNA pol μ siRNA (m) - sc-155886 from Santa Cruz Biotechnology
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DNA pol μ shRNA Plasmid (m) - sc-155886-SH from Santa Cruz Biotechnology
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DNA pol μ shRNA (m) Lentiviral Particles - sc-155886-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU008001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN39026 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39026 from Sigma-Aldrich
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POLM siRNA (Mouse) - CRM5441 from Cohesion Biosciences
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shRNA set against Mouse POLM (NM_017401.2) - SHH379288 from Creative biogene
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POLM shRNA Plasmid (Mouse) - CHM5441 from Cohesion Biosciences
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