Gene Symbol | Dao |
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Entrez Gene | 114027 |
Alt Symbol | Dao1 |
Species | Rat |
Gene Type | protein-coding |
Description | D-amino-acid oxidase |
Other Description | D-amino acid oxidase 1|DAAO|DAMOX |
Swissprots | O35078 |
Accessions | EDM13954 EDM13955 EDM13956 EDM13957 O35078 AB003400 BAA22840 BC088395 AAH88395 NM_053626 NP_446078 |
Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. |
Subcellular Location | Peroxisome. |
Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |
Recombinant Rat D-amino-acid oxidase(Dao) - CSB-YP006494RA CSB-EP006494RA CSB-BP006494RA CSB-MP006494RA from Cusabio
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Recombinant Rat DAO Protein - DAO-1773R from Creative Biomart
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D-amino-acid oxidase (Dao), Recombinant Protein - MBS1065423 from MyBioSource
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Recombinant Rat DAO Protein (1-346 aa), His-Myc-tagged - DAO-2573R from Creative Biomart
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