| Gene Symbol | Nsf |
|---|---|
| Entrez Gene | 60355 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | N-ethylmaleimide-sensitive factor |
| Other Description | N-ethylmaleimide sensitive factor|N-ethylmaleimide sensitive fusion protein|N-ethylmaleimide-sensitive fusion protein|NEM-sensitive fusion protein|vesicle-fusing ATPase|vesicular-fusion protein NSF |
| Swissprots | Q9QUL6 |
| Accessions | EDM06287 EDM06288 Q9QUL6 AF089839 AAC63035 AF091834 AAC61595 AF142097 AAD39485 AF189019 AAF01051 FQ211783 NM_021748 NP_068516 |
| Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. |
| Subcellular Location | Cytoplasm {ECO:0000250}. |
| Tissue Specificity | Detected in brain (at protein level). {ECO:0000269|PubMed:16461345}. |
| Top Pathways | Vasopressin-regulated water reabsorption, Synaptic vesicle cycle, GABAergic synapse |
NSF siRNA (r) - sc-156016 from Santa Cruz Biotechnology
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NSF shRNA Plasmid (r) - sc-156016-SH from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN58181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND58181 from Sigma-Aldrich
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NSF siRNA (Rat) - CRR1677 from Cohesion Biosciences
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shRNA set against Rat NSF (NM_021748.1) - SHH355340 from Creative biogene
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shRNA set against Rat Nsf(NM_021748.1) - SHR023422 from Creative biogene
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NSF shRNA Plasmid (Rat) - CHR1677 from Cohesion Biosciences
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NSF miRNA 3'UTR clone - MiUTR1R-04299 from Creative biogene
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