PPP2R5B

Gene Symbol	PPP2R5B
Entrez Gene	5526
Alt Symbol	B56B, PR61B
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 2, regulatory subunit B', beta
Other Description	PP2A B subunit isoform B'-beta|PP2A B subunit isoform B56-beta|PP2A B subunit isoform PR61-beta|PP2A B subunit isoform R5-beta|protein phosphatase 2, regulatory subunit B', beta isoform|serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform|serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Swissprots	Q13853 Q15173
Accessions	EAW74324 EAW74325 Q15173 AK092730 BC045619 AAH45619 BE883575 BM665417 EU446998 ABZ92527 L42374 AAC37602 XM_006718607 XP_006718670 XM_011545132 XP_011543434 XM_011545133 XP_011543435 XM_011545134 XP_011543436 NM_006244 NP_006235
Function	The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues. {ECO:0000269|PubMed:21329884}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:8703017}.
Tissue Specificity	Highest expression in brain.
Top Pathways	Oocyte meiosis, mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human PPP2R5B full length protein - ab131823 from Abcam Category Protein Source Wheat germ Species Human

Human PPP2R5B peptide - ab22848 from Abcam Category Peptide Species Human

PPP2R5B Antibody Blocking Peptide - LS-E25267 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PPP2R5B Protein - H00005526-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PPP2R5B Peptide - AC21-0095-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PPP2R5B - H00005526-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PPP2R5B - H00005526-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

B56 beta Peptide - 45-312P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

PPP2R5B fusion protein - ag7377 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform(PPP2R5B) - CSB-YP624017HU CSB-EP624017HU CSB-BP624017HU CSB-MP624017HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PPP2R5B - TP306889 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

B56 beta isoform, Peptide - MBS426407 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

PPP2R5B Recombinant Protein Antigen - NBP1-88958PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PPP2R5B-Blocking-Peptide-C-term - BP20958c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPP2R5B Peptide, Human - M34GP12281H from Creative Peptides Category Peptide Source Synthetic. Species Human

PPP2R5B fusion protein - Ag25928 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PPP2R5B), Recombinant Protein - MBS1442921 from MyBioSource Category Protein Prices $1,285.00, $1,285.00, $1,500.00, $1,500.00, $2,105.00, $2,105.00, $2,570.00, $2,570.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PPP2R5B Immunizing peptide - orb17602 from Biorbyt Category Peptide

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