CHST10

Gene Symbol CHST10
Entrez Gene 9486
Alt Symbol HNK-1ST, HNK1ST
Species Human
Gene Type protein-coding
Description carbohydrate sulfotransferase 10
Other Description HNK-1 sulfotransferase|huHNK-1ST
Swissprots O43529 Q53T18
Accessions AAX93044 CAJ75915 CBY88424 EAX01841 EAX01842 EAX01843 EAX01844 O43529 AF003827 AF033827 AAC04707 AF070594 AAC28651 AK297267 BAH12534 AK313241 BAG36052 AU124707 BC010441 AAH10441 BU849869 DA522916 DA732392 DQ891064 ABM81990 DQ894245 ABM85171 XM_011512207 XP_011510509 XM_011512208 XP_011510510 XM_011512209 XP_011510511 XM_011512210 XP_011510512 XM_011512211 XP_011510513 XM_011512212 XP_011510514 NM_004854 NP_004845
Function Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis. {ECO:0000269|PubMed:9478973}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe. {ECO:0000269|PubMed:9478973}.
Top Pathways Other types of O-glycan biosynthesis

HNK-1ST (N-14) - sc-49035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNK-1ST (N-14): sc-49035. Western blot analysis of HNK-1ST expression in MOLT-4 (A), Ramos (B) and SK-N-MC (C) whole cell lysates.

HNK-1ST (E-20) - sc-49034 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HNK-1ST (C-12) - sc-49032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HNK-1ST (E-16) - sc-49033 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HNK-1ST (H-237) - sc-367842 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HNK-1ST (H-237): sc-367842. Western blot analysis of HNK-1ST expression in mouse brain tissue extract.

Anti-CHST10 antibody - ab92648 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHST10 antibody (ab92648) at 1/500 dilutionLane 1 : Extract from HuvEc cells (without competing peptide)Lane 2 : Extract from HuvEc cells (with competing peptide)Lysates/proteins at 5 µg per lane.

Anti-CHST10 antibody - ab199638 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue labeling CHST10 with ab199638 at 1/50 dilution.

Anti-CHST10 antibody - C-terminal - ab173123 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CHST10 antibody - C-terminal (ab173123) at 1/100 dilution + HL-60 cell line lysate at 35 µg

Anti-CHST10 Antibody (aa207-236, APC) - LS-C254820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST10 Antibody (aa207-236, AP) - LS-C254821 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST10 Antibody (aa207-236, Azide-free, HRP) - LS-C254825 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST10 Antibody (aa207-236, Biotin) - LS-C254823 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST10 Antibody (aa207-236, FITC) - LS-C254824 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST10 Antibody (aa207-236, PE) - LS-C254826 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST10 Antibody (aa207-236) - LS-C320377 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST10 Antibody (aa207-236) - LS-C159349 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CHST10 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The CHST10 antibody detected the CHST10 protein (arrow).

Anti-CHST10 Antibody (aa191-240) - LS-C119803 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human lung carcinoma tissue, using CHST10 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CHST10 Antibody (C-Terminus) - LS-C345291 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of CHST10 Antibody with Jurkat Whole Cell lysate.

Carbohydrate Sulfotransferase 10/CHST10 Antibody - NBP1-81727 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Carbohydrate Sulfotransferase 10/CHST10 Antibody [NBP1-81727] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

Anti-CHST10 antibody produced in rabbit - HPA012884 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CHST10: <B>Cat. No. HPA012884</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human duodenum shows strong cytoplasmic positivity in glandular cells.

ANTI-CHST10(C-TERMINAL) antibody produced in rabbit - SAB1305150 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHST10 (C-term): <B>Cat. No. SAB1305150</B>: CHST10 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35 μg/lane).

Anti-CHST10 antibody produced in rabbit - SAB4503652 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CHST10: <B>Cat. No. SAB4503652</B>: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Anti-CHST10 antibody. Cells on the left were treated with the Anti-CHST10 antibody. Cells on the right (negative control) were treated with both Anti-CHST10 antibody and the synthesized immunogen peptide.

CHST10 Antibody - C-terminal region (ARP73702_P050) - ARP73702_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CHST10-Antibody-C-term - AP17499b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
CHST10 Antibody (C-term) (Cat. #AP17499b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CHST10 antibody detected the CHST10 protein (arrow).

CHST10-Antibody - AP50588 from Abgent, a WuXi AppTec company

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from human brain tissue lysate,using CHST10 Antibody(AP50588). AP50588 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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