Gene Symbol | Gpx3 |
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Entrez Gene | 14778 |
Alt Symbol | AA960521, EGPx, GPx, GSHPx-3, GSHPx-P |
Species | Mouse |
Gene Type | protein-coding |
Description | glutathione peroxidase 3 |
Other Description | GPx-3|GPx-P|extracellular GPx|plasma GPx|plasma glutathione peroxidase |
Swissprots | Q5XKR0 P46412 |
Accessions | EDL33515 EDL33516 EDL33517 EDL33518 EDL33519 P46412 AA062309 AI194448 AK002219 BAC55243 AK002262 AK004942 BAC55250 AK146760 BAE27413 BC003339 AAH03339 BC037027 AAH37027 BC037134 BC049235 AAH49235 BC061950 AAH61950 BY061328 BY100863 BY339672 CB601893 U13705 AAA62283 NM_008161 NP_032187 NM_001083929 |
Function | Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. |
Subcellular Location | Secreted. |
Tissue Specificity | Secreted in plasma. |
Top Pathways | Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |
GPx-3 CRISPR/Cas9 KO Plasmid (m) - sc-420664 from Santa Cruz Biotechnology
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GPx-3 HDR Plasmid (m) - sc-420664-HDR from Santa Cruz Biotechnology
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GPx-3 Double Nickase Plasmid (m) - sc-420664-NIC from Santa Cruz Biotechnology
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GPx-3 Double Nickase Plasmid (m2) - sc-420664-NIC-2 from Santa Cruz Biotechnology
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GPx-3 CRISPR Activation Plasmid (m) - sc-420664-ACT from Santa Cruz Biotechnology
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GPx-3 CRISPR Activation Plasmid (m2) - sc-420664-ACT-2 from Santa Cruz Biotechnology
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GPx-3 Lentiviral Activation Particles (m) - sc-420664-LAC from Santa Cruz Biotechnology
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GPx-3 Lentiviral Activation Particles (m2) - sc-420664-LAC-2 from Santa Cruz Biotechnology
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GPx-3 siRNA (m) - sc-62418 from Santa Cruz Biotechnology
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GPx-3 shRNA Plasmid (m) - sc-62418-SH from Santa Cruz Biotechnology
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GPx-3 shRNA (m) Lentiviral Particles - sc-62418-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU082251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN32803 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32803 from Sigma-Aldrich
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GPX3 siRNA (Mouse) - CRM1669 from Cohesion Biosciences
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GPX3 - MBS8201726 from MyBioSource
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GPX3 shRNA Plasmid (Mouse) - CHM1669 from Cohesion Biosciences
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