Gene Symbol | SEC24A |
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Entrez Gene | 10802 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | SEC24 family member A |
Other Description | SEC24 family, member A|SEC24 related gene family, member A|SEC24-related protein A|protein transport protein Sec24A |
Swissprots | A8MVW3 Q96GP7 Q8WUV2 O95486 |
Accessions | EAW62245 EAW62246 O95486 AJ131244 CAA10334 AK026545 AK304060 BAG64967 AL080064 AL137677 BC009325 AAH09325 BC019341 AAH19341 BM127845 CD109783 CD677660 XM_006714523 XP_006714586 XR_948228 NM_001252231 NP_001239160 NM_021982 NP_068817 |
Function | Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. |
Tissue Specificity | Expressed in fibroblasts, hepatocytes, and lymphocytes. |
Top Pathways | Protein processing in endoplasmic reticulum |
SEC24A CRISPR/Cas9 KO Plasmid (h) - sc-407059 from Santa Cruz Biotechnology
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SEC24A HDR Plasmid (h) - sc-407059-HDR from Santa Cruz Biotechnology
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SEC24A Double Nickase Plasmid (h) - sc-407059-NIC from Santa Cruz Biotechnology
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SEC24A Double Nickase Plasmid (h2) - sc-407059-NIC-2 from Santa Cruz Biotechnology
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SEC24A CRISPR Activation Plasmid (h) - sc-407059-ACT from Santa Cruz Biotechnology
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SEC24A CRISPR Activation Plasmid (h2) - sc-407059-ACT-2 from Santa Cruz Biotechnology
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SEC24A Lentiviral Activation Particles (h) - sc-407059-LAC from Santa Cruz Biotechnology
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SEC24A Lentiviral Activation Particles (h2) - sc-407059-LAC-2 from Santa Cruz Biotechnology
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SEC24A siRNA (h) - sc-270321 from Santa Cruz Biotechnology
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SEC24A shRNA Plasmid (h) - sc-270321-SH from Santa Cruz Biotechnology
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SEC24A shRNA (h) Lentiviral Particles - sc-270321-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU086671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19033 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19033 from Sigma-Aldrich
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SEC24A siRNA (Human) - CRH7362 from Cohesion Biosciences
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SEC24A - MBS8214475 from MyBioSource
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shRNA set against Human SEC24A (NM_021982.2) - SHH403804 from Creative biogene
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Human SEC24A siRNA - orb267864 from Biorbyt
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SEC24A shRNA Plasmid (Human) - CHH7362 from Cohesion Biosciences
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