Gene Symbol | GABRA3 |
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Entrez Gene | 2556 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
Other Description | GABA(A) receptor subunit alpha-3|GABA(A) receptor, alpha 3|gamma-aminobutyric acid receptor subunit alpha-3|gamma-animobutyric acid (GABA) A receptor, alpha 3 |
Swissprots | P34903 Q8TAF9 |
Accessions | AAG12455 EAW99423 P34903 A28102 CAA01919 AK312404 BAG35318 BC028629 AAH28629 DA402645 DQ892408 ABM83334 DQ895621 ABM86547 KJ620007 S62908 AAB27279 XM_005274659 XP_005274716 XM_006724811 XP_006724874 XM_011531133 XP_011529435 XM_011531134 XP_011529436 NM_000808 NP_000799 |
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
GABA A Rα3 CRISPR/Cas9 KO Plasmid (h) - sc-403044 from Santa Cruz Biotechnology
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GABA A Rα3 HDR Plasmid (h) - sc-403044-HDR from Santa Cruz Biotechnology
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GABA A Rα3 Double Nickase Plasmid (h) - sc-403044-NIC from Santa Cruz Biotechnology
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GABA A Rα3 Double Nickase Plasmid (h2) - sc-403044-NIC-2 from Santa Cruz Biotechnology
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GABA A Rα3 CRISPR Activation Plasmid (h) - sc-403044-ACT from Santa Cruz Biotechnology
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GABA A Rα3 CRISPR Activation Plasmid (h2) - sc-403044-ACT-2 from Santa Cruz Biotechnology
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GABA A Rα3 Lentiviral Activation Particles (h) - sc-403044-LAC from Santa Cruz Biotechnology
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GABA A Rα3 Lentiviral Activation Particles (h2) - sc-403044-LAC-2 from Santa Cruz Biotechnology
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GABA A Rα3 siRNA (h) - sc-42429 from Santa Cruz Biotechnology
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GABA A Rα3 shRNA Plasmid (h) - sc-42429-SH from Santa Cruz Biotechnology
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GABA A Rα3 shRNA (h) Lentiviral Particles - sc-42429-V from Santa Cruz Biotechnology
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GABA A R alpha 3 RNAi - H00002556-R01 from Novus Biologicals
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MISSION® esiRNA - EHU038321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1820 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1820 from Sigma-Aldrich
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GABRA3 siRNA (Human) - CRH1694 from Cohesion Biosciences
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GABRA3 - MBS8201308 from MyBioSource
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shRNA set against Human GABRA3 (NM_000808.3) - SHH298461 from Creative biogene
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shRNA set against Human GABRA3(NM_000808.3) - SHH073775 from Creative biogene
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Human GABRA3 siRNA - orb262196 from Biorbyt
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GABRA3 shRNA Plasmid (Human) - CHH1694 from Cohesion Biosciences
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GABRA3 miRNA 3'UTR clone - MiUTR1H-03911 from Creative biogene
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