| Gene Symbol |
Ppt1
|
| Entrez Gene |
29411
|
| Alt Symbol |
Ppt
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
palmitoyl-protein thioesterase 1
|
| Other Description |
PPT-1|palmitoyl-protein hydrolase 1
|
| Swissprots |
P45479 A0JN20
|
| Accessions |
EDL80359 EDL80360 P45479 BC126089 AAI26090 FQ213474 FQ213911 L34262 AAA59358 NM_022502 NP_071947
|
| Function |
Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
|
| Subcellular Location |
Lysosome.
|
| Tissue Specificity |
Highest amounts in brain, testis, lung, and spleen. Lowest amounts in liver and skeletal muscle.
|
| Top Pathways |
Lysosome, Fatty acid elongation, Fatty acid metabolism
|