C4BPA

Gene Symbol C4BPA
Entrez Gene 722
Alt Symbol C4BP, PRP
Species Human
Gene Type protein-coding
Description complement component 4 binding protein, alpha
Other Description C4b-binding protein alpha chain|proline-rich protein
Swissprots Q5VVQ8 P04003
Accessions AAA36506 CAA27839 CAB51244 EAW93500 EAW93501 EAW93502 EAW93503 P04003 AK303793 BAG64750 AK303798 BAG64753 AK313164 BAG35982 BC022312 AAH22312 BQ019292 DQ892021 ABM82947 DQ895213 ABM86139 M31452 AAA36507 X02865 CAA26617 X07853 CAA30701 XM_005273251 XP_005273308 XM_005273252 XP_005273309 NM_000715 NP_000706
Function Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Subcellular Location Secreted.
Tissue Specificity Chylomicrons in the plasma.
Top Pathways Complement and coagulation cascades, Pertussis

C4BP (GMA-036) - sc-65970 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

C4BPα (D-5) - sc-398720 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
C4BPα (D-5): sc-398720. Western blot analysis of C4BPα expression in HeLa whole cell lysate (A) and human liver tissue extract (B).

C4BPα (H-198) - sc-292601 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
C4BPα (H-198): sc-292601. Western blot analysis of C4BPα expression in A431 (A), WiDR (B), MCF7 (C), A549 (D) and HeLa (E) whole cell lysates and human liver tissue extract (F).

C4BPα (M-53) - sc-292602 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
C4BPα (M-53): sc-292602. Western blot analysis of C4BPα expression in WiDR (A), MCF7 (B) and A549 (C) whole cell lysates.

C4BPα (N-20) - sc-17206 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
C4BPα (N-20): sc-17206. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Anti-C4BPA antibody - ab121123 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C4BPA antibody (ab121123) at 1/250 dilutionLane 1 : RT4 cell lysateLane 2 : U-251 MG cell lysateLane 3 : A431 cell lysateLane 4 : Human Liver lysateLane 5 : Human Tonsil lysatedeveloped using the ECL technique

Anti-C4BPA antibody - ab121141 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C4BPA antibody (ab121141) at 1/250 dilutionLane 1 : Negative control (vector only transfected HEK293T lysate) Lane 2 : Over-expression Lysate [Co-expressed with a C-terminal proprietary tag (3.1 KDa)] in mammalian HEK293T cells

Anti-C4BPA antibody - ab167357 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-C4BPA antibody (ab167357) at 1 µg/mlLane 1 : C4BPA transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 25 µg per lane.SecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-C4BPA antibody [EPR14780] - ab200345 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14780
Anti-C4BPA antibody [EPR14780] (ab200345) at 1/5000 dilution + human plasma lysate at 20 µgSecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-C4BPA antibody [EPR14781(B)] - C-terminal - ab182140 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14781(B)
Anti-C4BPA antibody [EPR14781(B)] - C-terminal (ab182140) at 1/10000 dilution + Human plasma lysate at 20 µgSecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-C4BPA / C4BP Alpha Antibody (aa477-507, APC) - LS-C253164 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa477-507, Biotin) - LS-C253165 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa477-507, Azide-free, HRP) - LS-C253167 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa477-507, AP) - LS-C253163 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa477-507, FITC) - LS-C253166 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa477-507, PE) - LS-C253168 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa358-469, Biotin) - LS-C300390 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa358-469, FITC) - LS-C302327 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa548-597, Biotin) - LS-C299564 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa548-597, FITC) - LS-C304424 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody - LS-C309665 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa477-507) - LS-C319945 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPA / C4BP Alpha Antibody (aa548-597) - LS-C293075 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant C4BPA / C4BP.

Anti-C4BPA / C4BP Alpha Antibody (aa358-469) - LS-C293077 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant C4BPA / C4BP.

Anti-C4BPA / C4BP Alpha Antibody (aa470-499) IHC-plus™ - LS-B10567 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-C4BPA / C4BP antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10567 dilution 1:100.
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