Gene Symbol | TAS2R41 |
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Entrez Gene | 259287 |
Alt Symbol | T2R41, T2R59 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 41 |
Other Description | taste receptor type 2 member 41|taste receptor type 2 member 59 |
Swissprots | Q50KJ6 P59550 Q645W7 Q495I2 Q50KJ5 Q50KJ7 P59536 |
Accessions | AAM19323 AAM63543 BAD98051 BAD98052 BAD98053 CAI53583 CAI53585 P59536 BC101157 AAI01158 BC101158 AAI01159 NM_176883 NP_795364 |
Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
Top Pathways | Taste transduction |
T2R41 CRISPR/Cas9 KO Plasmid (h) - sc-415267 from Santa Cruz Biotechnology
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T2R41 HDR Plasmid (h) - sc-415267-HDR from Santa Cruz Biotechnology
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T2R41 Double Nickase Plasmid (h) - sc-415267-NIC from Santa Cruz Biotechnology
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T2R41 Double Nickase Plasmid (h2) - sc-415267-NIC-2 from Santa Cruz Biotechnology
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T2R41 CRISPR Activation Plasmid (h) - sc-415267-ACT from Santa Cruz Biotechnology
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T2R41 CRISPR Activation Plasmid (h2) - sc-415267-ACT-2 from Santa Cruz Biotechnology
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T2R41 Lentiviral Activation Particles (h) - sc-415267-LAC from Santa Cruz Biotechnology
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T2R41 Lentiviral Activation Particles (h2) - sc-415267-LAC-2 from Santa Cruz Biotechnology
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T2R41 siRNA (h) - sc-89717 from Santa Cruz Biotechnology
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T2R41 shRNA Plasmid (h) - sc-89717-SH from Santa Cruz Biotechnology
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T2R41 shRNA (h) Lentiviral Particles - sc-89717-V from Santa Cruz Biotechnology
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TAS2R41 RNAi - H00259287-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21026 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21026 from Sigma-Aldrich
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TAS2R41 siRNA (Human) - CRJ6811 from Cohesion Biosciences
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TAS2R41 - MBS8207265 from MyBioSource
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shRNA set against Human TAS2R41 (NM_176883.2) - SHH423560 from Creative biogene
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shRNA set against Human TAS2R41(NM_176883.2) - SHL057666 from Creative biogene
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TAS2R41 shRNA Plasmid (Human) - CHJ6811 from Cohesion Biosciences
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TAS2R41 miRNA 3'UTR clone - MiUTR1H-10199 from Creative biogene
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