Gene Symbol | MEK1 |
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Entrez Gene | 828713 |
Alt Symbol | ATMEK1, F20B18.180, F20B18_180, MAP kinase/ ERK kinase 1, MITOGEN ACTIVATED PROTEIN KINASE KINASE, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1, MKK1, NMAPKK |
Species | Arabidopsis thaliana |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase 1 |
Other Description | - |
Swissprots | Q94A06 O04661 O04440 |
Accessions | AEE85152 AEE85153 AEE85154 CAB39672 CAB79462 Q94A06 AB004796 BAA24079 AF000977 AAB97145 AY050774 AAK92709 AY087065 AAM64626 BT001935 AAN71934 NM_118740 NP_194337 NM_179115 NP_849446 NM_202890 NP_974619 |
Function | MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Activates by phosphorylation the downstream MPK4. Acts redundantly with MKK2. MKK1-MPK6 module mediates abscisic acid (ABA)-dependent CAT1 expression with H(2)O(2) production and response to drought and salt stress. MKK1-MPK6 module is also involved in sugar signaling during the process of seed germination. {ECO:0000269|PubMed:10759527, ECO:0000269|PubMed:17059410, ECO:0000269|PubMed:17728292, ECO:0000269|PubMed:18248592, ECO:0000269|PubMed:18599650, ECO:0000269|PubMed:18982020, ECO:0000269|PubMed:19484493}. |
Tissue Specificity | Expressed in roots, stem, flowers and siliques. {ECO:0000269|PubMed:9426629}. |
Top Pathways | Plant-pathogen interaction |
Recombinant Arabidopsis thaliana Mitogen-activated protein kinase kinase 1(MKK1 - CSB-YP013409DOA CSB-EP013409DOA CSB-BP013409DOA CSB-MP013409DOA from Cusabio
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Mitogen Activated Protein Kinase Kinase 1, Recombinant Protein - MBS2030594 from MyBioSource
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Mitogen-activated protein kinase kinase 1 (MKK1), Recombinant Protein - MBS1412179 from MyBioSource
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