Gene Symbol | LIPK |
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Entrez Gene | 643414 |
Alt Symbol | LIPL2, bA186O14.2 |
Species | Human |
Gene Type | protein-coding |
Description | lipase, family member K |
Other Description | lipase K|lipase member K|lipase-like abhydrolase domain-containing protein 2|lipase-like, ab-hydrolase domain containing 2 |
Swissprots | Q5VXJ0 A7KIH8 |
Accessions | Q5VXJ0 BC152924 AAI52925 EF426482 ABR08387 XM_011540072 XP_011538374 XM_011540073 XP_011538375 XM_011540074 XP_011538376 XM_011540075 XP_011538377 XM_011540076 XP_011538378 XM_011540077 XP_011538379 XM_011540078 XP_011538380 XM_011540079 XP_011538381 XM_011540080 XP_011538382 XM_011540081 XP_011538383 XM_011540082 XP_011538384 XR_945800 NM_001080518 NP_001073987 |
Function | Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. {ECO:0000269|PubMed:17562024}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Exclusively expressed in the epidermis within the granular keratinocytes. {ECO:0000269|PubMed:17562024}. |
LIPK CRISPR/Cas9 KO Plasmid (h) - sc-416111 from Santa Cruz Biotechnology
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LIPK HDR Plasmid (h) - sc-416111-HDR from Santa Cruz Biotechnology
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LIPK Double Nickase Plasmid (h) - sc-416111-NIC from Santa Cruz Biotechnology
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LIPK Double Nickase Plasmid (h2) - sc-416111-NIC-2 from Santa Cruz Biotechnology
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LIPK CRISPR Activation Plasmid (h) - sc-416111-ACT from Santa Cruz Biotechnology
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LIPK CRISPR Activation Plasmid (h2) - sc-416111-ACT-2 from Santa Cruz Biotechnology
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LIPK Lentiviral Activation Particles (h) - sc-416111-LAC from Santa Cruz Biotechnology
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LIPK Lentiviral Activation Particles (h2) - sc-416111-LAC-2 from Santa Cruz Biotechnology
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LIPK siRNA (h) - sc-90704 from Santa Cruz Biotechnology
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LIPK shRNA Plasmid (h) - sc-90704-SH from Santa Cruz Biotechnology
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LIPK shRNA (h) Lentiviral Particles - sc-90704-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU160841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11748 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11748 from Sigma-Aldrich
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LIPK siRNA (Human) - CRJ8456 from Cohesion Biosciences
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shRNA set against Human LIPK(NM_001080518.1) - SHH151211 from Creative biogene
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Human LIPK siRNA - orb278957 from Biorbyt
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LIPK shRNA Plasmid (Human) - CHJ8456 from Cohesion Biosciences
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LIPK miRNA 3'UTR clone - MiUTR1H-05701 from Creative biogene
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