Gene Symbol | Fut9 |
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Entrez Gene | 14348 |
Alt Symbol | AI746471, AU067636, mFUT9, mFuc-TIX |
Species | Mouse |
Gene Type | protein-coding |
Description | fucosyltransferase 9 |
Other Description | alpha-(1,3)-fucosyltransferase 9|fuc-TIX|fucT-IX|fucosyltransferase IX|galactoside 3-L-fucosyltransferase |
Swissprots | O88819 Q3TQ63 |
Accessions | EDL05524 O88819 AB015426 BAA33522 AK032177 BAC27746 AK033607 AK036183 BAC29338 AK037018 AK043410 BAC31540 AK047650 BAC33112 AK047668 AK049122 BAC33555 AK049167 BAC33583 AK085009 AK085273 AK137644 AK139133 AK162330 AK163871 BAE37522 BB626126 BC116874 AAI16875 BC116876 AAI16877 NM_010243 NP_034373 |
Function | Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. {ECO:0000269|PubMed:9756916}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}. |
Tissue Specificity | Mainly detected in brain and kidney. {ECO:0000269|PubMed:9756916}. |
Top Pathways | Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series |
FucT-IX CRISPR/Cas9 KO Plasmid (m) - sc-420427 from Santa Cruz Biotechnology
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FucT-IX HDR Plasmid (m) - sc-420427-HDR from Santa Cruz Biotechnology
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FucT-IX Double Nickase Plasmid (m) - sc-420427-NIC from Santa Cruz Biotechnology
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FucT-IX Double Nickase Plasmid (m2) - sc-420427-NIC-2 from Santa Cruz Biotechnology
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FucT-IX CRISPR Activation Plasmid (m) - sc-420427-ACT from Santa Cruz Biotechnology
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FucT-IX CRISPR Activation Plasmid (m2) - sc-420427-ACT-2 from Santa Cruz Biotechnology
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FucT-IX Lentiviral Activation Particles (m) - sc-420427-LAC from Santa Cruz Biotechnology
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FucT-IX Lentiviral Activation Particles (m2) - sc-420427-LAC-2 from Santa Cruz Biotechnology
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FucT-IX siRNA (m) - sc-40591 from Santa Cruz Biotechnology
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FucT-IX shRNA Plasmid (m) - sc-40591-SH from Santa Cruz Biotechnology
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FucT-IX shRNA (m) Lentiviral Particles - sc-40591-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU074051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN31609 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31609 from Sigma-Aldrich
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FUT9 siRNA (Mouse) - CRM1437 from Cohesion Biosciences
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FUT9 - MBS8229705 from MyBioSource
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shRNA set against Mouse FUT9 (NM_010243.3) - SHH297845 from Creative biogene
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shRNA set against Mouse Fut9(NM_010243.3) - SHH070931 from Creative biogene
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FucT-IX CRISPR/Cas9 KO Plasmid (m2) - sc-420427-KO-2 from Santa Cruz Biotechnology
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FucT-IX HDR Plasmid (m2) - sc-420427-HDR-2 from Santa Cruz Biotechnology
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Mouse FUT9 siRNA - orb280913 from Biorbyt
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FUT9 shRNA Plasmid (Mouse) - CHM1437 from Cohesion Biosciences
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FUT9 miRNA 3'UTR clone - MiUTR1M-04836 from Creative biogene
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