Gene Symbol | NDUFA6 |
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Entrez Gene | 4700 |
Alt Symbol | B14, CI-B14, LYRM6, NADHB14 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa |
Other Description | Complex I-B14|LYR motif-containing protein 6|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6|NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 6|NADH-ubiquinone oxidoreductase B14 subunit|complex I B14 subunit |
Swissprots | Q6IBT8 B2RE54 Q6IC39 Q6FGW0 O43675 P56556 |
Accessions | EAW60489 P56556 AF047182 AAC04267 AK291874 BAF84563 AK316562 BAG38151 BC002772 AAH02772 CR456529 CAG30415 CR456714 CAG32995 CR541997 CAG46794 CU013129 CAK54560 CU013417 CAK54859 DQ892966 ABM83892 DQ896214 ABM87213 NM_002490 NP_002481 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFA6 CRISPR/Cas9 KO Plasmid (h) - sc-405991 from Santa Cruz Biotechnology
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NDUFA6 HDR Plasmid (h) - sc-405991-HDR from Santa Cruz Biotechnology
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NDUFA6 Double Nickase Plasmid (h) - sc-405991-NIC from Santa Cruz Biotechnology
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NDUFA6 Double Nickase Plasmid (h2) - sc-405991-NIC-2 from Santa Cruz Biotechnology
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NDUFA6 CRISPR Activation Plasmid (h) - sc-405991-ACT from Santa Cruz Biotechnology
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NDUFA6 CRISPR Activation Plasmid (h2) - sc-405991-ACT-2 from Santa Cruz Biotechnology
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NDUFA6 Lentiviral Activation Particles (h) - sc-405991-LAC from Santa Cruz Biotechnology
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NDUFA6 Lentiviral Activation Particles (h2) - sc-405991-LAC-2 from Santa Cruz Biotechnology
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NDUFA6 siRNA (h) - sc-75889 from Santa Cruz Biotechnology
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NDUFA6 shRNA Plasmid (h) - sc-75889-SH from Santa Cruz Biotechnology
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NDUFA6 shRNA (h) Lentiviral Particles - sc-75889-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15144 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15144 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05605 from Sigma-Aldrich
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NDUFA6 siRNA (Human) - CRH3114 from Cohesion Biosciences
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NDUFA6 RNAi - H00004700-R01 from Novus Biologicals
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shRNA set against Human NDUFA6 (NM_002490.3) - SHH350576 from Creative biogene
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Human NDUFA6 siRNA - orb263616 from Biorbyt
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NDUFA6 shRNA Plasmid (Human) - CHH3114 from Cohesion Biosciences
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NDUFA6 miRNA 3'UTR clone - MiUTR1H-06698 from Creative biogene
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