Gene Symbol | GEM |
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Entrez Gene | 2669 |
Alt Symbol | KIR |
Species | Human |
Gene Type | protein-coding |
Description | GTP binding protein overexpressed in skeletal muscle |
Other Description | GTP-binding mitogen-induced T-cell protein|GTP-binding protein GEM|GTP-binding protein overexpressed in skeletal muscle|RAS-like protein KIR|kinase-inducible Ras-like protein |
Swissprots | B2RA31 P55040 |
Accessions | EAW91709 EAW91710 P55040 AK314017 BAG36728 BC022010 AAH22010 BI759640 DB018783 DQ890821 ABM81747 DQ893976 ABM84902 U10550 AAA64911 U13052 AAC50067 NM_005261 NP_005252 NM_181702 NP_859053 |
Function | Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. |
Subcellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
Tissue Specificity | Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle. |
Gem CRISPR/Cas9 KO Plasmid (h) - sc-406393 from Santa Cruz Biotechnology
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Gem HDR Plasmid (h) - sc-406393-HDR from Santa Cruz Biotechnology
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Gem Double Nickase Plasmid (h) - sc-406393-NIC from Santa Cruz Biotechnology
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Gem Double Nickase Plasmid (h2) - sc-406393-NIC-2 from Santa Cruz Biotechnology
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Gem CRISPR Activation Plasmid (h) - sc-406393-ACT from Santa Cruz Biotechnology
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Gem CRISPR Activation Plasmid (h2) - sc-406393-ACT-2 from Santa Cruz Biotechnology
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Gem Lentiviral Activation Particles (h) - sc-406393-LAC from Santa Cruz Biotechnology
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Gem Lentiviral Activation Particles (h2) - sc-406393-LAC-2 from Santa Cruz Biotechnology
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Gem siRNA (h) - sc-41719 from Santa Cruz Biotechnology
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Gem shRNA Plasmid (h) - sc-41719-SH from Santa Cruz Biotechnology
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Gem shRNA (h) Lentiviral Particles - sc-41719-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU049371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9227 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9227 from Sigma-Aldrich
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GEM siRNA (Human) - CRH1778 from Cohesion Biosciences
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GEM - MBS828116 from MyBioSource
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shRNA set against Human GEM (NM_005261.3) - SHH300454 from Creative biogene
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Human GEM siRNA - orb262280 from Biorbyt
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GEM shRNA Plasmid (Human) - CHH1778 from Cohesion Biosciences
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GEM miRNA 3'UTR clone - MiUTR3H-03165 from Creative biogene
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GEM miRNA 3'UTR clone - MiUTR3H-03166 from Creative biogene
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