Gene Symbol | ATP6V1B2 |
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Entrez Gene | 526 |
Alt Symbol | ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 |
Other Description | H+ transporting two-sector ATPase|V-ATPase B2 subunit|V-ATPase subunit B 2|V-type proton ATPase subunit B, brain isoform|endomembrane proton pump 58 kDa subunit|vacuolar H+-ATPase 56,000 subunit|vacuolar proton pump subunit B 2 |
Swissprots | Q96IR0 Q15859 Q14544 P21281 D3DSQ5 B2R5Z3 |
Accessions | CAA85522 CBX47579 EAW63758 EAW63759 P21281 AB208806 BAD92043 AK127443 AK294163 BAG57486 AK298819 BAG60951 AK312372 BAG35290 BC003100 AAH03100 BC007309 AAH07309 BC030640 AAH30640 DQ891837 ABM82763 DQ895023 ABM85949 L35249 AAA58661 M60346 AAA35610 X62949 CAA44721 NM_001693 NP_001684 |
Function | Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Subcellular Location | Endomembrane system; Peripheral membrane protein. Melanosome. Note=Endomembrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |
V-ATPase B2 CRISPR/Cas9 KO Plasmid (h) - sc-401896 from Santa Cruz Biotechnology
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V-ATPase B2 HDR Plasmid (h) - sc-401896-HDR from Santa Cruz Biotechnology
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V-ATPase B2 Double Nickase Plasmid (h) - sc-401896-NIC from Santa Cruz Biotechnology
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V-ATPase B2 Double Nickase Plasmid (h2) - sc-401896-NIC-2 from Santa Cruz Biotechnology
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V-ATPase B2 CRISPR Activation Plasmid (h) - sc-401896-ACT from Santa Cruz Biotechnology
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V-ATPase B2 CRISPR Activation Plasmid (h2) - sc-401896-ACT-2 from Santa Cruz Biotechnology
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V-ATPase B2 Lentiviral Activation Particles (h) - sc-401896-LAC from Santa Cruz Biotechnology
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V-ATPase B2 Lentiviral Activation Particles (h2) - sc-401896-LAC-2 from Santa Cruz Biotechnology
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V-ATPase B2 siRNA (h) - sc-43517 from Santa Cruz Biotechnology
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V-ATPase B2 shRNA Plasmid (h) - sc-43517-SH from Santa Cruz Biotechnology
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V-ATPase B2 shRNA (h) Lentiviral Particles - sc-43517-V from Santa Cruz Biotechnology
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ATP6V1B2 RNAi - H00000526-R02 from Novus Biologicals
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MISSION® esiRNA - EHU030391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3728 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3728 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12606 from Sigma-Aldrich
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ATP6V1B2 siRNA (Human) - CRH0364 from Cohesion Biosciences
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ATP6V1B2 - MBS8236770 from MyBioSource
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shRNA set against Human ATP6V1B2(NM_001693.3) - SHG083733 from Creative biogene
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Human ATP6V1B2 siRNA - orb260866 from Biorbyt
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Mouse ATP6V1B2 siRNA - orb279785 from Biorbyt
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ATP6V1B2 shRNA Plasmid (Human) - CHH0364 from Cohesion Biosciences
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ATP6V1B2 miRNA 3'UTR clone - MiUTR1H-00716 from Creative biogene
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