| Gene Symbol | FRE6 |
|---|---|
| Entrez Gene | 850675 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | Fre6p |
| Other Description | - |
| Swissprots | D6VXV7 Q12473 |
| Accessions | DAA09273 Q12473 NM_001181871 NP_013049 |
| Function | Metalloreductase responsible for reducing vacuolar iron and copper prior to transport into the cytosol. Catalyzes the reduction of Fe(3+) to Fe(2+) and Cu(2+) to Cu(+), respectively, which can then be transported by the respective vacuolar efflux systems to the cytosol. {ECO:0000269|PubMed:17553781, ECO:0000269|PubMed:17681937}. |
| Subcellular Location | Vacuole membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17553781, ECO:0000269|PubMed:17681937}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17553781, ECO:0000269|PubMed:17681937}. |