| Gene Symbol |
FRE6
|
| Entrez Gene |
850675
|
| Alt Symbol |
-
|
| Species |
Yeast
|
| Gene Type |
protein-coding
|
| Description |
Fre6p
|
| Other Description |
-
|
| Swissprots |
D6VXV7 Q12473
|
| Accessions |
DAA09273 Q12473 NM_001181871 NP_013049
|
| Function |
Metalloreductase responsible for reducing vacuolar iron and copper prior to transport into the cytosol. Catalyzes the reduction of Fe(3+) to Fe(2+) and Cu(2+) to Cu(+), respectively, which can then be transported by the respective vacuolar efflux systems to the cytosol. {ECO:0000269|PubMed:17553781, ECO:0000269|PubMed:17681937}.
|
| Subcellular Location |
Vacuole membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17553781, ECO:0000269|PubMed:17681937}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17553781, ECO:0000269|PubMed:17681937}.
|