| Gene Symbol |
SENP5
|
| Entrez Gene |
205564
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SUMO1/sentrin specific peptidase 5
|
| Other Description |
SUMO1/sentrin specific protease 5|sentrin-specific protease 5|sentrin/SUMO-specific protease SENP5
|
| Swissprots |
Q96HI0 Q96SA5 B4DY82
|
| Accessions |
EAW53625 EAW53626 EAW53627 EAW53628 EAW53629 Q96HI0 AF335474 AAK69630 AK124389 AK302305 BAG63644 AK313764 BAG36502 AL049229 BC000958 BC008589 AAH08589 BC013799 BC030705 AAH30705 BC036626 DC399261 DQ890849 ABM81775 DQ894003 ABM84929 XM_005269310 XP_005269367 XM_005269311 XP_005269368 XM_005269312 XP_005269369 XM_011512544 XP_011510846 XM_011512545 XP_011510847 NM_001308045 NP_001294974 NM_152699 NP_689912
|
| Function |
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. {ECO:0000269|PubMed:16608850, ECO:0000269|PubMed:16738315}.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:16608850, ECO:0000269|PubMed:16738315}.
|
![Western Blot: SENP5 Overexpression Lysate (Adult Normal) [NBL1-15811] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SENP5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/19023_SENP5%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-15811-img0002.jpg)