Gene Symbol | PLBD1 |
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Entrez Gene | 79887 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase B domain containing 1 |
Other Description | LAMA-like protein 1|PLB homolog 1|lamina ancestor homolog 1|phospholipase B domain-containing protein 1|phospholipase B-like 1|putative phospholipase B-like 1 |
Swissprots | A8K4E9 Q9H625 Q9BVV3 Q6P4A8 |
Accessions | EAW96322 EAW96323 Q6P4A8 AI370813 AK026315 BAB15442 AK225458 AK290914 BAF83603 BC000909 AAH00909 BC063561 AAH63561 BQ721063 BU859334 CB993231 CD366142 NM_024829 NP_079105 |
Function | In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids. {ECO:0000250, ECO:0000269|PubMed:19019078}. |
Subcellular Location | Lysosome {ECO:0000250}. |
Tissue Specificity | Expressed in neutrophils and monocytes. {ECO:0000269|PubMed:19019078}. |
PLBD1 CRISPR/Cas9 KO Plasmid (h) - sc-413286 from Santa Cruz Biotechnology
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PLBD1 HDR Plasmid (h) - sc-413286-HDR from Santa Cruz Biotechnology
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PLBD1 Double Nickase Plasmid (h) - sc-413286-NIC from Santa Cruz Biotechnology
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PLBD1 Double Nickase Plasmid (h2) - sc-413286-NIC-2 from Santa Cruz Biotechnology
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PLBD1 CRISPR Activation Plasmid (h) - sc-413286-ACT from Santa Cruz Biotechnology
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PLBD1 CRISPR Activation Plasmid (h2) - sc-413286-ACT-2 from Santa Cruz Biotechnology
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PLBD1 Lentiviral Activation Particles (h) - sc-413286-LAC from Santa Cruz Biotechnology
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PLBD1 Lentiviral Activation Particles (h2) - sc-413286-LAC-2 from Santa Cruz Biotechnology
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PLBD1 siRNA (h) - sc-96121 from Santa Cruz Biotechnology
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PLBD1 shRNA Plasmid (h) - sc-96121-SH from Santa Cruz Biotechnology
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PLBD1 shRNA (h) Lentiviral Particles - sc-96121-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU037531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16918 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16918 from Sigma-Aldrich
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PLBD1 siRNA (Human) - CRJ2642 from Cohesion Biosciences
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shRNA set against Human PLBD1 (NM_024829.5) - SHH377084 from Creative biogene
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shRNA set against Human FLJ22662(NM_024829.5) - SHH062021 from Creative biogene
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Human PLBD1 siRNA - orb273143 from Biorbyt
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PLBD1 shRNA Plasmid (Human) - CHJ2642 from Cohesion Biosciences
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PLBD1 miRNA 3'UTR clone - MiUTR1H-03717 from Creative biogene
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