Gene Symbol | SPAG4 |
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Entrez Gene | 6676 |
Alt Symbol | CT127, SUN4 |
Species | Human |
Gene Type | protein-coding |
Description | sperm associated antigen 4 |
Other Description | SUN domain-containing protein 4|Sad1 and UNC84 domain containing 4|acrosomal protein ACR55|cancer/testis antigen 127|outer dense fiber-associated protein SPAG4|sperm tail protein|sperm-associated antigen 4 protein |
Swissprots | Q9NPE6 O43648 |
Accessions | AAC32052 AAF75268 CAB87609 EAW76191 Q9NPE6 AF262992 AAF75267 BC111378 AAI11379 BC143783 XM_005260519 XP_005260576 XM_005260520 XP_005260577 XM_011529009 XP_011527311 XM_011529010 XP_011527312 XM_011529011 XP_011527313 NM_003116 NP_003107 |
Function | May assist the organization and assembly of outer dense fibers (ODFs), a specific structure of the sperm tail. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250}. Note=In spermatids, it is localized in the transient manchette and in the axoneme of elongating spermatids and epididymal sperm. {ECO:0000250}. |
SPAG4 CRISPR/Cas9 KO Plasmid (h) - sc-404154 from Santa Cruz Biotechnology
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SPAG4 HDR Plasmid (h) - sc-404154-HDR from Santa Cruz Biotechnology
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SPAG4 Double Nickase Plasmid (h) - sc-404154-NIC from Santa Cruz Biotechnology
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SPAG4 Double Nickase Plasmid (h2) - sc-404154-NIC-2 from Santa Cruz Biotechnology
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SPAG4 CRISPR Activation Plasmid (h) - sc-404154-ACT from Santa Cruz Biotechnology
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SPAG4 CRISPR Activation Plasmid (h2) - sc-404154-ACT-2 from Santa Cruz Biotechnology
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SPAG4 Lentiviral Activation Particles (h) - sc-404154-LAC from Santa Cruz Biotechnology
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SPAG4 Lentiviral Activation Particles (h2) - sc-404154-LAC-2 from Santa Cruz Biotechnology
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SPAG4 siRNA (h) - sc-76544 from Santa Cruz Biotechnology
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SPAG4 shRNA Plasmid (h) - sc-76544-SH from Santa Cruz Biotechnology
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SPAG4 shRNA (h) Lentiviral Particles - sc-76544-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU056681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20387 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20387 from Sigma-Aldrich
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SPAG4 siRNA (Human) - CRH4553 from Cohesion Biosciences
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SPAG4 - MBS8237917 from MyBioSource
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shRNA set against Human SPAG4 (NM_003116.1) - SHH415836 from Creative biogene
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shRNA set against Human SPAG4(NM_003116.1) - SHL025730 from Creative biogene
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Human SPAG4 siRNA - orb265055 from Biorbyt
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SPAG4 shRNA Plasmid (Human) - CHH4553 from Cohesion Biosciences
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SPAG4 miRNA 3'UTR clone - MiUTR1H-09794 from Creative biogene
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