| Gene Symbol |
LRRC59
|
| Entrez Gene |
55379
|
| Alt Symbol |
PRO1855, p34
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leucine rich repeat containing 59
|
| Other Description |
leucine-rich repeat-containing protein 59|ribosome-binding protein p34
|
| Swissprots |
D3DTX8 Q96AG4 Q9P189 B2RE83
|
| Accessions |
EAW94615 EAW94616 Q96AG4 AF119857 AAF69611 AK025328 AK130572 AK316593 BAG38180 BC017168 AAH17168 BC033695 BC052279 AAH52279 BM664133 DA782636 DQ579028 DQ892375 ABM83301 DQ895589 ABM86515 NM_018509 NP_060979
|
| Function |
Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. {ECO:0000269|PubMed:22321063}.
|
| Subcellular Location |
Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus envelope. Note=Localization in the nuclear envelope depends upon the nuclear import machinery, including KPNB1.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:11964394}.
|