| Gene Symbol | FUT6 |
|---|---|
| Entrez Gene | 2528 |
| Alt Symbol | FCT3A, FT1A, Fuc-TVI, FucT-VI |
| Species | Human |
| Gene Type | protein-coding |
| Description | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| Other Description | alpha-(1,3)-fucosyltransferase 6|fucosyltransferase VI|galactoside 3-L-fucosyltransferase |
| Swissprots | P51993 Q9UND8 D6W637 A6NEX0 |
| Accessions | AAB03078 EAW69136 EAW69137 EAW69138 EAW69139 P51993 AF131211 AAD33509 AK098073 AK225795 AK313130 BAG35950 BC040472 BC061700 AAH61700 DA426469 DA622182 DA628976 M98825 AAA99222 U27331 AAC50190 U27332 AAC50191 U27333 AAC50192 U27334 AAC50193 U27335 AAC50194 U27336 AAC50195 U27337 AAC50196 XM_005259526 XP_005259583 XM_005259527 XP_005259584 XM_011527868 XP_011526170 XM_011527869 XP_011526171 XM_011527870 XP_011526172 XM_011527871 XP_011526173 XM_011527872 XP_011526174 XM_011527873 XP_011526175 XM_011527874 XP_011526176 XM_011527875 XP_011526177 XM_011527876 XP_011526178 XM_011527877 XP_011526179 XM_011527878 XP_011526180 XM_011527879 XP_011526181 NM_000150 NP_000141 NM_001040701 NP_001035791 |
| Function | Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates. |
| Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. |
| Tissue Specificity | Kidney, liver, colon, small intestine, bladder, uterus and salivary gland. |
| Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |